Department of Obstetrics & Gynecology
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Protocols

 
MANAGEMENT GUIDELINE
 
Subject:           Neisseria Gonorrhea
 
Screening/Diagnosis:
 
1.         All patients should be screened at the New OB exam.
 
2.         All patients should be screened by 36 weeks gestation.  (State Guidelines)
 
3.         Sexual contact with possibly infected partner or suspicious cervical discharge (mucopurulent) noted during speculum exam
 
Recommendations:     
 
If the patient has a positive culture and is otherwise asymptomatic the following treatment options may be used: Check for penicillin allergy
Cefixime 400 mg orally in a single dose,
                          OR
 Ceftriaxone 125 mg IM in a single dose

Alternative Regimen:   Spectinomycin 2 g in a single, IM dose. Spectinomycin is expensive and must be injected; however, it has been effective in published clinical trials, curing 98.2% of uncomplicated urogenital and anorectal gonococcal infections. 
All patients need Azithromycin (Zithromax) 1 gm po x 1 for chlamydia coverage unless a negative test result is in hand.
 
If the patient has symptoms of disseminated GC (fever, low abdominal pain) she should be referred for evaluation.
 
Follow-up After Treatment:
 
  • An attempt to identify and treat the partner should be made.                
 
  • Counsel the patient on safe sex techniques.
 
  • Insure VDRL and Hepatitis B Surface Antigen have been obtained and HIV test has been offered. 
 
  • A test of cure culture may be obtained at the care providers discretion or by 36 weeks.
 
  • Patients should receive Hep B Vaccine
 
Prepared in conjunction with the
Division of Maternal-Fetal Medicine
Duke University Medical Center
 
                                                                        _____________________  __________
1/16/07                                                 Director                                    Date
 
                                                                       
 
 
                                                                                   

Reference

Neisseria Gonorrhea

 
1.         Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines 2006. MMWR 2006:55(No. RR-42-47)
 
 
 
 
The Clinical Care Guidelines Development Committee of the Perinatal Improvement Board of Duke University Health System has developed a series of multi-disciplinary protocols to offer guidance to health care providers who are caring for pregnant women with high risk conditions.
 
These protocols are designed to assist health care providers in the management of a variety of problems that occur in pregnancy and the time of delivery. They should not be interpreted as standard of care, but instead represent only general guidelines for the care of pregnant women with high risk conditions.  We recognize that services offered by individual providers depend not only on their training, experience and institutional resources, but on the medical facts and circumstances of the specific care situation.
The protocols remain the intellectual property of the Duke University Health System.  They cannot be reproduced in whole or part without the expressed permission of the Health System.
 
These protocols are reviewed by the Department of Obstetrics and Gynecology Division of Maternal-Fetal Medicine, the Department of Pediatrics Division of Neonatology and the Department of Anesthesiology Division of Women’s Anesthesia.  Please contact Andra H. James (andra.james@duke.edu), Chair, Clinical Care Guidelines Development Committee of the Perinatal Improvement Board with ideas for additional protocols.
 
 
 
 
 
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