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Amy Patricia Murtha, MD

Amy P Murtha, MD
Professor of Obstetrics and Gynecology
Campus Mail: 4022 Hosp South, Durham, NC 27710
Phone: (919) 681-5220
Email: murth002@mc.duke.edu

Dr. Amy Murtha is a Professor in the Department of Obstetrics and Gynecology and Department of Pediatrics, and Vice Chair for Research in Obstetrics and Gynecology. After graduating from the Medical College of Pennsylvania in 1992 she completed her residency in OB-GYN and fellowship in Maternal Fetal Medicine (MFM) at Duke University then joined the faculty at Duke in 1998. 

Dr. Murtha served as interim Chair for the Department of OB-GYN and Fellowship Director for the maternal fetal medicine division. She is currently Clinical Research Unit (CRU) Director and Program Director for the NIH-funded K12 training grant Building Interdisciplinary Research Careers in Women’s Health (BIRCWH).  As a leader in research administration, Dr. Murtha has created an environment for the oversight of research in a way that is beneficial to the entire enterprise.  

Dr. Murtha’s research career has focused primarily on preterm delivery and specifically on preterm premature rupture of membranes (PPROM).  As a clinician scientist, she has the unique perspective of understanding the clinical implications of both basic and laboratory research. The Perinatal Research Initiative, led by Dr. Murtha and funded through philanthropic dollars, has allowed for growth in the size and scope of her lab.  In addition to advancing the understanding of the etiology of preterm birth she has also focused on training the next generation of physician scientists in translational and molecular biology techniques with over 75 publications.  Dr. Murtha uses her experiences and leadership skills to create an environment of supportive, collaborative, financially responsible research at Duke that aligns with the missions of the School of Medicine and the Duke University Health System.  

Education and Training

  • Resident, Obstetrics & Gynecology, Duke University, 1992 - 1996
  • M.D., Drexel University, 1992
Vice Chair Discipline: 
Research

Publications

Ahmadzia, HK, Thomas, SM, Murtha, AP, Heine, RP, and Brancazio, LR. "Obstetric hemorrhage survey: Attitudes and practices of maternal-fetal medicine fellows." Journal of neonatal-perinatal medicine 9, no. 2 (May 17, 2016): 133-137.

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Potts, LC, Feng, L, Seed, PC, Jayes, FL, Kuchibhatla, M, Antczak, B, Nazzal, MK, and Murtha, AP. "Inflammatory Response of Human Gestational Membranes to Ureaplasma parvum Using a Novel Dual-Chamber Tissue Explant System." Biology of reproduction 94, no. 5 (May 2016): 119-.

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Riccio, DA, Malowitz, JR, Cotten, CM, Murtha, AP, and McMahon, TJ. "S-Nitrosylated fetal hemoglobin in neonatal human blood." Biochemical and biophysical research communications 473, no. 4 (May 2016): 1084-1089.

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Grotegut, CA, Mao, L, Pierce, SL, Swamy, GK, Heine, RP, and Murtha, AP. "Enhanced Uterine Contractility and Stillbirth in Mice Lacking G Protein-Coupled Receptor Kinase 6 (GRK6): Implications for Oxytocin Receptor Desensitization." Molecular endocrinology (Baltimore, Md.) 30, no. 4 (April 2016): 455-468.

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Kim, E, Allen, TK, Feng, L, Nazzal, MK, and Murtha, AP. "The Effect of Cytokines on Neutrophil Gelatinase-Associated Lipocalin (NGAL) mRNA Expression in a Cytotrophoblast Cell Line." March 2016.

Scholars@Duke

McCullough, LE, Miller, EE, Mendez, MA, Murtha, AP, Murphy, SK, and Hoyo, C. "Maternal B vitamins: effects on offspring weight and DNA methylation at genomically imprinted domains." Clinical epigenetics 8 (January 22, 2016): 8-.

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Potts, LC, Feng, L, Jayes, FL, and Murtha, AP. "341: Novel ex vivo system to evaluate inflammation of gestational membranes in response to U. parvum." January 2016.

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Fuemmeler, BF, Lee, C-T, Soubry, A, Iversen, ES, Huang, Z, Murtha, AP, Schildkraut, JM, Jirtle, RL, Murphy, SK, and Hoyo, C. "DNA Methylation of Regulatory Regions of Imprinted Genes at Birth and Its Relation to Infant Temperament." Genetics & epigenetics 8 (January 2016): 59-67.

Scholars@Duke

Feng, L, Ouyang, F, Liu, L, Wang, X, Wang, X, Li, Y-J, Murtha, A, Shen, H, Zhang, J, and Zhang, JJ. "Levels of Urinary Metabolites of Organophosphate Flame Retardants, TDCIPP, and TPHP, in Pregnant Women in Shanghai." Journal of environmental and public health 2016 (January 2016): 9416054-.

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Feng, L, Ransom, CE, Nazzal, MK, Allen, TK, Li, Y-J, Truong, T, Potts, LC, Seed, PC, and Murtha, AP. "The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection." PloS one 11, no. 12 (January 2016): e0168102-.

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