Murtha, AP, Nieves, A, Hauser, ER, Swamy, GK, Yonish, BA, Sinclair, TR, and Heine, RP. "Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth." Am J Obstet Gynecol 195, no. 5 (November 2006): 1249-1253.
Amy Patricia Murtha, MD
Dr. Amy Murtha is a Professor in the Department of Obstetrics and Gynecology and Department of Pediatrics, and Vice Chair for Research in Obstetrics and Gynecology. After graduating from the Medical College of Pennsylvania in 1992 she completed her residency in OB-GYN and fellowship in Maternal Fetal Medicine (MFM) at Duke University then joined the faculty at Duke in 1998.
Dr. Murtha served as interim Chair for the Department of OB-GYN and Fellowship Director for the maternal fetal medicine division. She is currently Clinical Research Unit (CRU) Director and Program Director for the NIH-funded K12 training grant Building Interdisciplinary Research Careers in Women’s Health (BIRCWH). As a leader in research administration, Dr. Murtha has created an environment for the oversight of research in a way that is beneficial to the entire enterprise.
Dr. Murtha’s research career has focused primarily on preterm delivery and specifically on preterm premature rupture of membranes (PPROM). As a clinician scientist, she has the unique perspective of understanding the clinical implications of both basic and laboratory research. The Perinatal Research Initiative, led by Dr. Murtha and funded through philanthropic dollars, has allowed for growth in the size and scope of her lab. In addition to advancing the understanding of the etiology of preterm birth she has also focused on training the next generation of physician scientists in translational and molecular biology techniques with over 75 publications. Dr. Murtha uses her experiences and leadership skills to create an environment of supportive, collaborative, financially responsible research at Duke that aligns with the missions of the School of Medicine and the Duke University Health System.
Education and Training
- Resident, Obstetrics & Gynecology, Duke University, 1992 - 1996
- M.D., Drexel University, 1992
Selected Grants and Awards
- Building Interdisciplinary Research Careers in Women's Health
- Effects of perfluorobutane sulfonate (PFBS) exposure on adverse pregnancy outcomes and fetal development
- Endocrinology and Metabolism Training Program
- Novel Coherence Imaging to Evaluate the Health of the Cervical Epithelium
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program
- Hypoxic Ischemic Encephalopathy-Phase II-Robertson Foundation
- Role of the Vaginal Microbiome in Preterm Birth
- Novel Determination of Microbicide PK in Women's Reproductive Health
- Role of GRK6-Mediated Oxytocin Receptor Desensitization in Labor
- Obesity and deregulation of imprinted genes in early life
- Pregnancy Outcomes and 17P
- Nutrition, Deregulation of Imprinted Genes
- Preterm Delivery Impacts Reproductive Health: Understanding the Etiology
- In-utero Exposure and Infant Loss of IGF2 Imprinting
- Neuromuscular Injury and Recovery after Vaginal Delivery
Mills, AA, Yonish, B, Feng, L, Schomberg, DW, Heine, RP, and Murtha, AP. "Characterization of progesterone receptor isoform expression in fetal membranes." Am J Obstet Gynecol 195, no. 4 (October 2006): 998-1003.
Murtha, AP, Kaplan, AL, Paglia, MJ, Mills, BB, Feldstein, ML, and Ruff, GL. "Evaluation of a novel technique for wound closure using a barbed suture." Plast Reconstr Surg 117, no. 6 (May 2006): 1769-1780.
Boggess, KA, Beck, JD, Murtha, AP, Moss, K, and Offenbacher, S. "Maternal periodontal disease in early pregnancy and risk for a small-for-gestational-age infant." Am J Obstet Gynecol 194, no. 5 (May 2006): 1316-1322.
Ruma, MS, Boggess, KA, Moss, K, Beck, J, Jared, H, Murtha, AP, and Offenbacher, S. "Maternal periodontal disease, systemic inflammation and risk for preeclampsia." February 2006.
Boggess, KA, Moss, K, Murtha, A, Offenbacher, S, and Beck, JD. "Antepartum vaginal bleeding, fetal exposure to oral pathogens, and risk for preterm birth at <35 weeks of gestation." American Journal of Obstetrics and Gynecology 194, no. 4 (2006): 954-960.
Muller, PR, James, AH, Murtha, AP, Yonish, B, Jamison, MG, and Dekker, G. "Circulating angiogenic factors and abnormal uterine artery Doppler velocimetry in the second trimester." Hypertens Pregnancy 25, no. 3 (2006): 183-192.
Offenbacher, S, Boggess, KA, Murtha, AP, Jared, HL, Lieff, S, McKaig, RG, Mauriello, SM, Moss, KL, and Beck, JD. "Progressive periodontal disease and risk of very preterm delivery." Obstet Gynecol 107, no. 1 (January 2006): 29-36.
Boggess, KA, Moss, K, Madianos, P, Murtha, AP, Beck, J, and Offenbacher, S. "Fetal immune response to oral pathogens and risk of preterm birth." Am J Obstet Gynecol 193, no. 3 Pt 2 (September 2005): 1121-1126.
Boggess, KA, Lieff, S, Murtha, AP, Moss, K, Jared, H, Beck, J, and Offenbacher, S. "Maternal serum C-reactive protein concentration early in pregnancy and subsequent pregnancy loss." Am J Perinatol 22, no. 6 (August 2005): 299-304.