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Amy Patricia Murtha, MD

Amy P Murtha, MD
Professor of Obstetrics and Gynecology
Campus Mail: 4022 Hosp South, Durham, NC 27710
Phone: (919) 681-5220
Email: murth002@mc.duke.edu

Dr. Amy Murtha is a Professor in the Department of Obstetrics and Gynecology and Department of Pediatrics, and Vice Chair for Research in Obstetrics and Gynecology. After graduating from the Medical College of Pennsylvania in 1992 she completed her residency in OB-GYN and fellowship in Maternal Fetal Medicine (MFM) at Duke University then joined the faculty at Duke in 1998. 

Dr. Murtha served as interim Chair for the Department of OB-GYN and Fellowship Director for the maternal fetal medicine division. She is currently Clinical Research Unit (CRU) Director and Program Director for the NIH-funded K12 training grant Building Interdisciplinary Research Careers in Women’s Health (BIRCWH).  As a leader in research administration, Dr. Murtha has created an environment for the oversight of research in a way that is beneficial to the entire enterprise.  

Dr. Murtha’s research career has focused primarily on preterm delivery and specifically on preterm premature rupture of membranes (PPROM).  As a clinician scientist, she has the unique perspective of understanding the clinical implications of both basic and laboratory research. The Perinatal Research Initiative, led by Dr. Murtha and funded through philanthropic dollars, has allowed for growth in the size and scope of her lab.  In addition to advancing the understanding of the etiology of preterm birth she has also focused on training the next generation of physician scientists in translational and molecular biology techniques with over 75 publications.  Dr. Murtha uses her experiences and leadership skills to create an environment of supportive, collaborative, financially responsible research at Duke that aligns with the missions of the School of Medicine and the Duke University Health System.  

Education and Training

  • Resident, Obstetrics & Gynecology, Duke University, 1992 - 1996
  • M.D., Drexel University, 1992
Vice Chair Discipline: 
Research

Publications

Allen, TK, Feng, L, Grotegut, CA, and Murtha, AP. "Progesterone receptor membrane component 1 as the mediator of the inhibitory effect of progestins on cytokine-induced matrix metalloproteinase 9 activity in vitro." Reprod Sci 21, no. 2 (February 2014): 260-268.

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Murtha, AP, Fortner, KB, Grotegut, CA, Ransom, CE, Bentley, RC, Feng, L, Lan, L, Heine, RP, and Seed, PC. "Bacteria Localization and Chorion Thinning among Preterm Premature Rupture of Membranes." PLoS One (January 8, 2014). (Academic Article)

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Kraus, DM, Feng, L, Heine, RP, Brown, HL, Caron, KM, Murtha, AP, and Grotegut, CA. "Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion." Reprod Sci 21, no. 1 (January 2014): 63-71.

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Cotten, CM, Murtha, AP, Goldberg, RN, Grotegut, CA, Smith, PB, Goldstein, RF, Fisher, KA, Gustafson, KE, Waters-Pick, B, Swamy, GK, Rattray, B, Tan, S, and Kurtzberg, J. "Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy." Journal of Pediatrics 164, no. 5 (January 1, 2014).

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Vidal, AC, Benjamin Neelon, SE, Liu, Y, Tuli, AM, Fuemmeler, BF, Hoyo, C, Murtha, AP, Huang, Z, Schildkraut, J, Overcash, F, Kurtzberg, J, Jirtle, RL, Iversen, ES, and Murphy, SK. "Maternal stress, preterm birth, and DNA methylation at imprint regulatory sequences in humans." Genetics & epigenetics 6 (January 2014): 37-44.

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Matson, BC, Corty, RW, Karpinich, NO, Murtha, AP, Valdar, W, Grotegut, CA, and Caron, KM. "Midregional pro-adrenomedullin plasma concentrations are blunted in severe preeclampsia." Placenta 35, no. 9 (January 1, 2014): 780-783.

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Feng, L, Antczak, BC, Lan, L, Grotegut, CA, Thompson, JL, Allen, TK, and Murtha, AP. "Progesterone receptor membrane component 1 (PGRMC1) expression in fetal membranes among women with preterm premature rupture of the membranes (PPROM)." Placenta 35, no. 5 (January 1, 2014): 331-333.

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Murtha, AP, and Edwards, JM. "The role of Mycoplasma and Ureaplasma in adverse pregnancy outcomes." Obstetrics and Gynecology Clinics of North America 41, no. 4 (January 1, 2014): 615-627. (Review)

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Grotegut, CA, Gunatilake, RP, Feng, L, Heine, RP, and Murtha, AP. "The influence of maternal body mass index on myometrial oxytocin receptor expression in pregnancy." Reprod Sci 20, no. 12 (December 2013): 1471-1477.

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Canzoneri, BJ, Feng, L, Grotegut, CA, Bentley, RC, Heine, RP, and Murtha, AP. "The chorion layer of fetal membranes is prematurely destroyed in women with preterm premature rupture of the membranes." Reprod Sci 20, no. 10 (October 2013): 1246-1254.

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