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Andrew Berchuck, MD

Andrew Berchuck, MD
James M. Ingram Professor of Gynecologic Oncology
Campus Mail: 25171 Morris Bldg, Durham, NC 27710
Phone: (919) 684-3765
Email: berch001@mc.duke.edu

Dr. Andrew Berchuck is Director of the Duke Division of Gynecologic Oncology and holds the James M. Ingram Distinguished Professorship. He is a practicing oncologist who is actively involved in the surgical and chemotherapy management of women with ovarian, endometrial and lower genital tract cancers. This includes minimally invasive laparoscopic surgical approaches. He also has developed a research program that focuses on the molecular-genetic alterations involved in malignant transformation of the ovarian and endometrial epithelium. He has published over 300 peer-reviewed papers in these areas. The objectives of his research include 1) identification of ovarian cancer susceptibility polymorphisms through a population-based case-control molecular epidemiologic study, and 2) use of genomic approaches  to elucidate the molecular heterogenetity of ovarian cancer. Thirty fellows and residents have worked in his lab, several of whom are now funded investigators. His research efforts have been recognized nationally and he has received awards for best oral presentation at the annual meetings of both the Society of Gynecologic Oncology and the International Gynecologic Cancer Society. Dr. Berchuck was awarded the Barbara Thomason Ovarian Cancer Research Professorship by the American Cancer Society in 2006. He has served as editor of several books in the field including Principles and Practice of Gynecologic Oncology. Dr. Berchuck also has a major commitment to national activities, and was President of the Society of Gynecologic Oncology in 2008. He served as chair of the scientific advisory committee of the Ovarian Cancer Research Fund (http://www.ocrf.org) in New York City. Finally, he is also head of the steering committee of the international Ovarian Cancer Association Consortium (OCAC), a group of 50 case-control studies that are working together to identify ovarian cancer susceptibility polymorphisms (www.srl.cam.ac.uk/consortia/ocac/index.html).

Education and Training

  • M.D., Case Western Reserve University, 1980

Research

Dr Berchuck is interested in the molecular pathogenesis of ovarian and endometrial cancer. 

View Publications

Selected Grants and Awards

Publications

Berchuck, A, Kohler, MF, Marks, JR, Wiseman, R, Boyd, J, and Jr, RCB. "The p53 tumor suppressor gene frequently is altered in gynecologic cancers." American Journal of Obstetrics and Gynecology 170, no. 1 I (1994): 246-252.

Scholars@Duke

Berchuck, A, Kohler, MF, Marks, JR, Wiseman, R, Boyd, J, and Bast, RC. "The p53 tumor suppressor gene frequently is altered in gynecologic cancers." Am J Obstet Gynecol 170, no. 1 Pt 1 (January 1994): 246-252. (Review)

Scholars@Duke

BERCHUCK, A, KOHLER, MF, MARKS, JR, WISEMAN, R, BOYD, J, and BAST, RC. "THE P53 TUMOR-SUPPRESSOR GENE FREQUENTLY IS ALTERED IN GYNECOLOGIC CANCERS." AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 170, no. 1 (January 1994): 246-252.

Scholars@Duke

Berchuck, A, and Dodge, RK. "Interval to treatment in endometrial cancer." Am J Obstet Gynecol 169, no. 6 (December 1993): 1655-1656. (Letter)

Scholars@Duke

Leopold, KA, Oleson, JR, Clarke-Pearson, D, Soper, J, Berchuck, A, Samulski, TV, Page, RL, Blivin, J, Tomberlin, JK, and Dewhirst, MW. "Intraperitoneal cisplatin and regional hyperthermia for ovarian carcinoma." Int J Radiat Oncol Biol Phys 27, no. 5 (December 1, 1993): 1245-1251.

Scholars@Duke

Soisson, AP, Olt, G, Soper, JT, Berchuck, A, Rodriguez, G, and Clarke-Pearson, DL. "Prevention of superficial wound separation with subcutaneous retention sutures." Gynecol Oncol 51, no. 3 (December 1993): 330-334.

Full Text

Woolas, RP, Xu, FJ, Jacobs, IJ, Yu, YH, Daly, L, Berchuck, A, Soper, JT, Clarke-Pearson, DL, Oram, DH, and Bast, RC. "Elevation of multiple serum markers in patients with stage I ovarian cancer." Journal of the National Cancer Institute 85, no. 21 (November 1993): 1748-1751.

Full Text

Risinger, JI, Berchuck, A, Kohler, MF, Watson, P, Lynch, HT, and Boyd, J. "Genetic instability of microsatellites in endometrial carcinoma." Cancer Res 53, no. 21 (November 1, 1993): 5100-5103.

Scholars@Duke

Kohler, MF, Marks, JR, Wiseman, RW, Jacobs, IJ, Davidoff, AM, Clarke-Pearson, DL, Soper, JT, Bast, RC, and Berchuck, A. "Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer." J Natl Cancer Inst 85, no. 18 (September 15, 1993): 1513-1519.

Scholars@Duke

BOYD, J, KOHLER, MF, BERCHUCK, A, WATSON, P, LYNCH, HT, and RISINGER, JI. "MICROSATELLITE INSTABILITY IN SPORADIC ENDOMETRIAL CARCINOMAS AND THOSE ASSOCIATED WITH HNPCC." AMERICAN JOURNAL OF HUMAN GENETICS 53, no. 3 (September 1993): 22-22.

Scholars@Duke

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