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Chad Aaron Grotegut, MD

Chad Grotegut, MD
Associate Professor of Obstetrics and Gynecology
Campus Mail: Box 3967 Med Ctr, Durham, NC 27710
Phone: (919) 681-5220
Email: chad.grotegut@duke.edu

Desensitization of the oxytocin receptor as an etiology for dysfunction labor and post-partum hemorrhage. The molecular mechanisms of preeclampsia and the protective role of cigarette smoke exposure.

Education and Training

  • Obstetrics & Gynecology, Maternal Fetal Medicine, Duke University, 2006 - 2009
  • Residency, Obstetrics & Gynecology, Duke University, 1999 - 2003
  • M.D., Temple University, 1999

Certifications

  • American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology, Maternal-Fetal Medicine

Research

Dr. Grotegut conducts both basic science/laboratory research, as well as participate in running clinical studies.  His laboratory research interests primarily focus on the hormone oxytocin and in understanding the mechanisms of uterine contractility.  This work is translated then to the clinical care of women through studies dedicated to understanding normal and abnormal labor.  In addition to his work in labor, he is involved in understanding the role that medical conditions and complications have in pregnancy outcomes.     

PubMed

Google Scholar

 

Publications

Smrtka, MP, Feng, L, Murtha, AP, and Grotegut, CA. "Thrombin-Induced Inflammation in Human Decidual Cells Is Not Affected By Heparin." Reproductive Sciences (Thousand Oaks, Calif.) 24, no. 8 (August 2017): 1154-1163.

Full Text

Feldman, CH, Grotegut, CA, and Rosenberg, PB. "The role of STIM1 and SOCE in smooth muscle contractility." Cell calcium 63 (May 2017): 60-65. (Review)

Full Text

Wood, AM, Post, AL, Swamy, GK, and Grotegut, CA. "Implications of non-cephalic presentation in preterm delivery." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Wood, AM, Post, AL, Swamy, GK, and Grotegut, CA. "Implications of non-cephalic presentation in preterm delivery." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Edwards, J, Truong, T, Li, Y-J, Grotegut, CA, and Murtha, AP. "MMP activation in human fetal membranes by TNF-alpha and Ureaplasma parvum." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Edwards, J, Truong, T, Li, Y-J, Grotegut, CA, and Murtha, AP. "MMP activation in human fetal membranes by TNF-alpha and Ureaplasma parvum." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Lee, PS, Kempner, S, Miller, M, Dominguez, J, Grotegut, C, Ehrisman, J, Previs, R, Havrilesky, LJ, Broadwater, G, Ellestad, SC, and Secord, AA. "Multidisciplinary approach to manage antenatally suspected placenta percreta: updated algorithm and patient outcomes." Gynecologic oncology research and practice 4 (January 2017): 11-.

Full Text

Villers, MS, Hopkins, MK, Harris, BS, Brancazio, LR, Grotegut, CA, and Heine, RP. "Negative pressure wound therapy reduces cesarean delivery surgical site infections in morbidly obese women." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Villers, MS, Hopkins, MK, Harris, BS, Brancazio, LR, Grotegut, CA, and Heine, RP. "Negative pressure wound therapy reduces cesarean delivery surgical site infections in morbidly obese women." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Villers, MS, Thomas, CH, Grotegut, CA, Heine, RP, and Swamy, GK. "Reduction of cesarean delivery surgical site infections using an evidence-based care bundle." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

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