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Chad Aaron Grotegut, MD

Chad Grotegut, MD
Associate Professor of Obstetrics and Gynecology
Campus Mail: Box 3967 Med Ctr, Durham, NC 27710
Phone: (919) 681-5220
Email: chad.grotegut@duke.edu

Desensitization of the oxytocin receptor as an etiology for dysfunction labor and post-partum hemorrhage. The molecular mechanisms of preeclampsia and the protective role of cigarette smoke exposure.

Education and Training

  • Obstetrics & Gynecology, Maternal Fetal Medicine, Duke University, 2006 - 2009
  • Residency, Obstetrics & Gynecology, Duke University, 1999 - 2003
  • M.D., Temple University, 1999

Certifications

  • American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology, Maternal-Fetal Medicine

Research

Dr. Grotegut conducts both basic science/laboratory research, as well as participate in running clinical studies.  His laboratory research interests primarily focus on the hormone oxytocin and in understanding the mechanisms of uterine contractility.  This work is translated then to the clinical care of women through studies dedicated to understanding normal and abnormal labor.  In addition to his work in labor, he is involved in understanding the role that medical conditions and complications have in pregnancy outcomes.     

PubMed

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Publications

Villers, MS, Thomas, CH, Grotegut, CA, Heine, RP, and Swamy, GK. "Reduction of cesarean delivery surgical site infections using an evidence-based care bundle." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Villers, MS, Thomas, CH, Grotegut, CA, Heine, RP, and Swamy, GK. "Reduction of cesarean delivery surgical site infections using an evidence-based care bundle." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Grotegut, CA, Ngan, E, Garrett, ME, Ashley-Koch, AE, and Swamy, GK. "Single nucleotide polymorphisms in the oxytocin receptor and GRK6 are associated with oxytocin dosing requirements and labor outcomes." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Grotegut, CA, Ngan, E, Garrett, ME, Ashley-Koch, AE, and Swamy, GK. "Single nucleotide polymorphisms in the oxytocin receptor and GRK6 are associated with oxytocin dosing requirements and labor outcomes." 37th Annual Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine (SMFM). Las Vegas, NV. January 23, 2017 - January 28, 2017.: MOSBY-ELSEVIER, January 1, 2017.

Scholars@Duke

Ahmadzia, HK, Lockhart, EL, Thomas, SM, Welsby, IJ, Hoffman, MR, James, AH, Murtha, AP, Swamy, GK, and Grotegut, CA. "Using antifibrinolytics in the peripartum period - concern for a hypercoagulable effect?." Journal of Neonatal Perinatal Medicine 10, no. 1 (January 2017): 1-7.

Full Text

Grotegut, CA. "Prevention of preeclampsia." The Journal of Clinical Investigation 126, no. 12 (December 2016): 4396-4398. (Review)

Full Text

James, AH, Grotegut, C, Ahmadzia, H, Peterson-Layne, C, and Lockhart, E. "Management of Coagulopathy in Postpartum Hemorrhage." Seminars in thrombosis and hemostasis 42, no. 7 (October 3, 2016): 724-731. (Review)

Full Text

Highley, LL, Previs, RA, Dotters-Katz, SK, Brancazio, LR, and Grotegut, CA. "Cesarean delivery among women with prolonged labor induction." Journal of Perinatal Medicine 44, no. 7 (October 2016): 759-766.

Full Text

Clowse, MEB, and Grotegut, C. "Racial and Ethnic Disparities in the Pregnancies of Women With Systemic Lupus Erythematosus." Arthritis care & research 68, no. 10 (October 2016): 1567-1572.

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Hill, CC, Lockhart, EL, Thames, E, Paglia, MJ, Small, MJ, James, AH, and Grotegut, CA. "Comparison of the trends in risk factors and management of severe postpartum hemorrhage: Years 2000–2004 versus 2005–2008." Journal of Reproductive Medicine 61, no. 4 (August 1, 2016): 320-326.

Scholars@Duke

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