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Chad Aaron Grotegut, MD

Chad Grotegut, MD
Associate Professor of Obstetrics and Gynecology
Campus Mail: Box 3967 Med Ctr, Durham, NC 27710
Phone: (919) 681-5220
Email: chad.grotegut@duke.edu

Desensitization of the oxytocin receptor as an etiology for dysfunction labor and post-partum hemorrhage. The molecular mechanisms of preeclampsia and the protective role of cigarette smoke exposure.

Education and Training

  • Obstetrics & Gynecology, Maternal Fetal Medicine, Duke University, 2006 - 2009
  • Residency, Obstetrics & Gynecology, Duke University, 1999 - 2003
  • M.D., Temple University, 1999

Certifications

  • American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology, Maternal-Fetal Medicine

Research

Dr. Grotegut conducts both basic science/laboratory research, as well as participate in running clinical studies.  His laboratory research interests primarily focus on the hormone oxytocin and in understanding the mechanisms of uterine contractility.  This work is translated then to the clinical care of women through studies dedicated to understanding normal and abnormal labor.  In addition to his work in labor, he is involved in understanding the role that medical conditions and complications have in pregnancy outcomes.     

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Publications

Wheeler, SM, Patel, E, Hopkins, M, Antczak, B, Grotegut, CA, and Swamy, GK. "Influence of Race and BMI on Cytokine Expression After Influenza Vaccination in Pregnancy." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016.

Scholars@Duke

Wheeler, SM, Patel, E, Hopkins, M, Antczak, B, Grotegut, CA, and Swamy, GK. "Influence of Race and BMI on Cytokine Expression After Influenza Vaccination in Pregnancy." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016.

Scholars@Duke

Brown, HL, Harris, B, and Grotegut, CA. "Seatbelt use during pregnancy." The American journal of emergency medicine 34, no. 2 (February 2016): 326-328. (Letter)

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Ahmadzia, HK, Grotegut, CA, and James, AH. "509: Rates of postpartum hemorrhage and related interventions: United States, 2000-2012." January 2016.

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Grotegut, CA, Chisholm, CA, Johnson, LNC, Brown, HL, Heine, RP, and James, AH. "Correction: Medical and Obstetric Complications among Pregnant Women Aged 45 and Older." PloS one 11, no. 3 (January 2016): e0151307-.

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Dotters-Katz, SK, Feldman, C, Puechl, A, Grotegut, CA, and Heine, RP. "Risk factors for post-operative wound infection in the setting of chorioamnionitis and cesarean delivery." The Journal of Maternal Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 29, no. 10 (January 2016): 1541-1545.

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Patil, AS, Swamy, GK, Murtha, AP, Heine, RP, Zheng, X, and Grotegut, CA. "Progesterone Metabolites Produced by Cytochrome P450 3A Modulate Uterine Contractility in a Murine Model." Reproductive sciences (Thousand Oaks, Calif.) 22, no. 12 (December 2015): 1577-1586.

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Wheeler, SM, Dotters-Katz, S, Heine, RP, Grotegut, CA, and Swamy, GK. "Maternal Effects of Respiratory Syncytial Virus Infection during Pregnancy." Emerging Infectious Diseases 21, no. 11 (November 2015): 1951-1955.

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Smrtka, MP, Gunatilake, RP, Harris, B, Yu, M, Lan, L, Brancazio, LR, Valea, FA, Grotegut, CA, and Brown, HL. "Increase in Cesarean Operative Time Following Institution of the 80-Hour Workweek." Journal of Graduate Medical Education 7, no. 3 (September 2015): 369-375.

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Thompson, JL, Kuklina, EV, Bateman, BT, Callaghan, WM, James, AH, and Grotegut, CA. "Medical and Obstetric Outcomes Among Pregnant Women With Congenital Heart Disease." Obstetrics and Gynecology 126, no. 2 (August 2015): 346-354.

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