Patel, EM, Swamy, GK, Heine, RP, Kuller, JA, James, AH, and Grotegut, CA. "Medical and obstetric complications among pregnant women with cystic fibrosis." American Journal of Obstetrics and Gynecology 212, no. 1 (January 1, 2015): 98e1-98e9.
Chad Aaron Grotegut, MD
Desensitization of the oxytocin receptor as an etiology for dysfunction labor and post-partum hemorrhage. The molecular mechanisms of preeclampsia and the protective role of cigarette smoke exposure.
Education and Training
- Obstetrics & Gynecology, Maternal Fetal Medicine, Duke University, 2006 - 2009
- Residency, Obstetrics & Gynecology, Duke University, 1999 - 2003
- M.D., Temple University, 1999
- American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
- American Board of Obstetrics and Gynecology, Maternal-Fetal Medicine
Dr. Grotegut conducts both basic science/laboratory research, as well as participate in running clinical studies. His laboratory research interests primarily focus on the hormone oxytocin and in understanding the mechanisms of uterine contractility. This work is translated then to the clinical care of women through studies dedicated to understanding normal and abnormal labor. In addition to his work in labor, he is involved in understanding the role that medical conditions and complications have in pregnancy outcomes.
Selected Grants and Awards
- Cellular and Molecular Systems Biology of Preterm Birth
- Obstructive Sleep Apnea Screening in Pregnant Women with Chronic Hypertension
- Pharmacokinetic and pharmacogenomics approach to indomethacin therapy in pregnancy
- Role of GRK6-Mediated Oxytocin Receptor Desensitization in Labor
Patel, EM, Swamy, GK, Heine, RP, Kuller, JA, James, AH, and Grotegut, CA. "Medical and obstetric complications among pregnant women with cystic fibrosis." January 2015.
Patel, EM, Goodnight, WH, James, AH, and Grotegut, CA. "Temporal trends in maternal medical conditions and stillbirth." American Journal of Obstetrics and Gynecology 212, no. 5 (2015): 673.e1-673.e11.
Matson, BC, Corty, RW, Karpinich, NO, Murtha, AP, Valdar, W, Grotegut, CA, and Caron, KM. "[305-POS]: Plasma concentrations of midregional pro-adrenomedullin are blunted in women with severe preeclampsia." Pregnancy hypertension 5, no. 1 (January 2015): 150-151.
Grotegut, CA, Kuklina, EV, Anstrom, KJ, Heine, RP, Callaghan, WM, Myers, ER, and James, AH. "Factors associated with the change in prevalence of cardiomyopathy at delivery in the period 2000-2009: a population-based prevalence study." BJOG : an international journal of obstetrics and gynaecology 121, no. 11 (October 2014): 1386-1394.
Ahmadzia, HK, Thomas, SM, Dude, AM, Grotegut, CA, and Boyd, BK. "Prediction of birthweight from third-trimester ultrasound in morbidly obese women." American journal of obstetrics and gynecology 211, no. 4 (October 2014): 431.e1-431.e7.
Reddick, KLB, Smrtka, MP, Grotegut, CA, James, AH, Brancazio, LR, and Swamy, GK. "The effects of intermittent pneumatic compression during cesarean delivery on fibrinolysis." American Journal of Perinatology 31, no. 9 (October 2014): 735-740.
Matson, BC, Corty, RW, Karpinich, NO, Murtha, AP, Valdar, W, Grotegut, CA, and Caron, KM. "Midregional pro-adrenomedullin plasma concentrations are blunted in severe preeclampsia." Placenta 35, no. 9 (September 2014): 780-783.
Abdul-Kadir, R, McLintock, C, Ducloy, A-S, El-Refaey, H, England, A, Federici, AB, Grotegut, CA, Halimeh, S, Herman, JH, Hofer, S, James, AH, Kouides, PA, Paidas, MJ, Peyvandi, F, and Winikoff, R. "Evaluation and management of postpartum hemorrhage: consensus from an international expert panel." Transfusion 54, no. 7 (July 2014): 1756-1768.
Cotten, CM, Murtha, AP, Goldberg, RN, Grotegut, CA, Smith, PB, Goldstein, RF, Fisher, KA, Gustafson, KE, Waters-Pick, B, Swamy, GK, Rattray, B, Tan, S, and Kurtzberg, J. "Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy." The Journal of Pediatrics 164, no. 5 (May 2014): 973-979.e1.