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Chad Aaron Grotegut, MD

Chad Grotegut, MD
Associate Professor of Obstetrics and Gynecology
Campus Mail: Box 3967 Med Ctr, Durham, NC 27710
Phone: (919) 681-5220
Email: chad.grotegut@duke.edu

Desensitization of the oxytocin receptor as an etiology for dysfunction labor and post-partum hemorrhage. The molecular mechanisms of preeclampsia and the protective role of cigarette smoke exposure.

Education and Training

  • Obstetrics & Gynecology, Maternal Fetal Medicine, Duke University, 2006 - 2009
  • Residency, Obstetrics & Gynecology, Duke University, 1999 - 2003
  • M.D., Temple University, 1999

Certifications

  • American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology, Maternal-Fetal Medicine

Research

Dr. Grotegut conducts both basic science/laboratory research, as well as participate in running clinical studies.  His laboratory research interests primarily focus on the hormone oxytocin and in understanding the mechanisms of uterine contractility.  This work is translated then to the clinical care of women through studies dedicated to understanding normal and abnormal labor.  In addition to his work in labor, he is involved in understanding the role that medical conditions and complications have in pregnancy outcomes.     

PubMed

Google Scholar

 

Publications

Canzoneri, BJ, Feng, L, Grotegut, CA, Bentley, RC, Heine, RP, and Murtha, AP. "The chorion layer of fetal membranes is prematurely destroyed in women with preterm premature rupture of the membranes." Reprod Sci 20, no. 10 (October 2013): 1246-1254.

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Limmer, JS, Grotegut, CA, Thames, E, Dotters-Katz, SK, Brancazio, LR, and James, AH. "Postpartum wound and bleeding complications in women who received peripartum anticoagulation." Thromb Res 132, no. 1 (July 2013): e19-e23.

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Luley, T, Fitzpatrick, CB, Grotegut, CA, Hocker, MB, Myers, ER, and Brown, HL. "Perinatal implications of motor vehicle accident trauma during pregnancy: identifying populations at risk." Am J Obstet Gynecol 208, no. 6 (June 2013): 466.e1-466.e5.

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Thompson, JL, Antczak, BC, Feng, L, Grotegut, CA, Seed, PC, and Murtha, AP. "Distribution of Toll-Like Receptor 4 in Preterm Fetal Membranes." March 2013.

Scholars@Duke

Smrtka, MP, Grotegut, CA, Feng, L, and Murtha, AP. "Thrombin-Induced Tissue Factor Expression in Human Decidual Cells Is Not Affected by Enoxaparin." March 2013.

Scholars@Duke

Luley, T, Fitzpatrick, CB, Grotegut, CA, Hocker, MB, Myers, ER, and Brown, HL. "Perinatal implications of motor vehicle accident trauma during pregnancy: Identifying populations at risk." American Journal of Obstetrics and Gynecology 208, no. 6 (2013): 466.e1-466.e5.

Full Text

Limmer, JS, Grotegut, CA, Thames, E, Dotters-Katz, SK, Brancazio, LR, and James, AH. "Postpartum wound and bleeding complications in women who received peripartum anticoagulation." Thrombosis Research 132, no. 1 (2013): e19-e23.

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Dotters-Katz, SK, Grotegut, CA, and Heine, RP. "The effects of anemia on pregnancy outcome in patients with pyelonephritis." Infect Dis Obstet Gynecol 2013 (2013): 780960-.

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Fletcher, S, Grotegut, CA, and James, AH. "Lochia patterns among normal women: a systematic review." J Womens Health (Larchmt) 21, no. 12 (December 2012): 1290-1294. (Review)

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Fortner, KB, Fitzpatrick, CB, Grotegut, CA, Swamy, GK, Murtha, AP, Heine, RP, and Brown, HL. "Cervical dilation as a predictor of pregnancy outcome following emergency cerclage." J Matern Fetal Neonatal Med 25, no. 10 (October 2012): 1884-1888.

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