Skip to main content

Chad Aaron Grotegut, MD

Chad Grotegut, MD
Associate Professor of Obstetrics and Gynecology
Campus Mail: Box 3967 Med Ctr, Durham, NC 27710
Phone: (919) 681-5220

Desensitization of the oxytocin receptor as an etiology for dysfunction labor and post-partum hemorrhage. The molecular mechanisms of preeclampsia and the protective role of cigarette smoke exposure.

Education and Training

  • Obstetrics & Gynecology, Maternal Fetal Medicine, Duke University, 2006 - 2009
  • Residency, Obstetrics & Gynecology, Duke University, 1999 - 2003
  • M.D., Temple University, 1999


  • American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology, Maternal-Fetal Medicine


Dr. Grotegut conducts both basic science/laboratory research, as well as participate in running clinical studies.  His laboratory research interests primarily focus on the hormone oxytocin and in understanding the mechanisms of uterine contractility.  This work is translated then to the clinical care of women through studies dedicated to understanding normal and abnormal labor.  In addition to his work in labor, he is involved in understanding the role that medical conditions and complications have in pregnancy outcomes.     


Google Scholar



Grotegut, CA, Paglia, MJ, Johnson, LNC, Thames, B, and James, AH. "Oxytocin exposure during labor among women with postpartum hemorrhage secondary to uterine atony." Am J Obstet Gynecol 204, no. 1 (January 2011): 56.e1-56.e6.

Full Text

Grotegut, CA, Moore, NL, Reddick, KL, Canzoneri, BJ, Boyd, BK, and Brown, HL. "Cervicovaginal fistula presenting during miscarriage." Ultrasound Obstet Gynecol 36, no. 1 (July 2010): 112-114.

Full Text

James, AH, Paglia, MJ, Gernsheimer, T, Grotegut, C, and Thames, B. "Blood component therapy in postpartum hemorrhage." Transfusion 49, no. 11 (November 2009): 2430-2433.

Full Text

Madan, I, Puri, I, Jain, NJ, Grotegut, C, Nelson, D, and Dandolu, V. "Characteristics of obstetric intensive care unit admissions in New Jersey." J Matern Fetal Neonatal Med 22, no. 9 (September 2009): 785-790.

Full Text

Shah, AA, Grotegut, CA, Likes, CE, Miller, MJ, and Walmer, DK. "Heterotopic cervical pregnancy treated with transvaginal ultrasound-guided aspiration resulting in cervical site varices within the myometrium." Fertil Steril 91, no. 3 (March 2009): 934.e19-934.e22.

Full Text

Geifman-Holtzman, O, Grotegut, CA, Gaughan, JP, Holtzman, EJ, Floro, C, and Hernandez, E. "Noninvasive fetal RhCE genotyping from maternal blood." BJOG 116, no. 2 (January 2009): 144-151. (Review)

Full Text

Grotegut, CA, Tatineni, H, Dandolu, V, Whiteman, VE, Katari, S, and Geifman-Holtzman, O. "Obstetric outcomes with a false-positive one-hour glucose challenge test by the Carpenter-Coustan criteria." J Matern Fetal Neonatal Med 21, no. 5 (May 2008): 315-320.

Full Text

Rose, MZ, Jeronis, SL, and Grotegut, CA. "Snowstorms and grape clusters." Am J Obstet Gynecol 198, no. 5 (May 2008): 605.e1-605.e2.

Full Text

Grotegut, CA, Fitzpatrick, CB, and Brancazio, LR. "A sudden pop." Am J Obstet Gynecol 198, no. 3 (March 2008): 340.e1-340.e2.

Full Text

Dandolu, V, Harmanli, OH, Grotegut, C, Turner, T, Hernandez, E, and Grody, MT. "Long-term Anatomic and Functional Outcome Following Sacrospinous Fixation Using Comprehensive Pelvic Floor Questionnaires." Journal of Pelvic Medicine and Surgery 13, no. 4 (July 2007): 177-180.

Full Text