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Friederike Luking Jayes, DVM, PhD

Property title
Assistant Professor of Obstetrics and Gynecology
Campus Mail: 238 Sands Building, Box 103209, Durham, NC 27710-3209
Phone: (919) 668-3973
Email: friederike.jayes@duke.edu

I received my Veterinary Medicine degree in Giessen, Germany and my PhD in Physiology from North Carolina State University in Raleigh. My research interests have always centered on the physiology and endocrinology of the female reproductive system. Uterine fibroids have a major impact on women’s health, on quality of life and on health cost. The etiology of this disease remains unknown and non-surgical therapies are either short-lived or have significant side effects. Good translational research is needed, combining the skills, backgrounds and visions of basic and clinical researchers. The Reproductive Biology and Perinatal Lab (RBPL) has a great mix of projects and includes clinical and basic researchers. The fibroid research within the lab embraces an entirely new direction in thinking about uterine fibroids. We are looking at fibroids as more than neoplasms, and consider them to be a fibrotic disease. I also love teaching and believe that it happens not only in the classroom but also in the laboratory. Our group works hard to invite and accommodate students, residents, and fellows. We teach not only methods and procedures, but also approaches, limitations and design of experiments in hypothesis driven research. This knowledge and experience will serve any future researcher and clinician well when reading the literature, asking their own questions, and during collaborations. As a team, we are on our way to make a difference in woman’s health.

Education and Training

  • Ph.D., North Carolina State University, 1995
  • D.V.M., Justus Liebig University Giessen (Germany), 1987

Publications

JAYES, FL, MILLER, WL, and BRITT, JH. "INHIBIN ALTERS LH-RELEASE AND FSH-RELEASE FROM PERIFUSED PORCINE PITUITARY-CELLS PULSED WITH GNRH." 1995.

Scholars@Duke

Heit, MC, Monteiro-Riviere, NA, Jayes, FL, and Riviere, JE. "Transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH): effect of repeated administration." Pharm Res 11, no. 7 (July 1994): 1000-1003.

Scholars@Duke

Heit, MC, Williams, PL, Jayes, FL, and Chang, SK. Erratum: Transdermal iontophoretic peptide delivery: In vitro and in vivo studies with luteinizing hormone releasing hormone (Journal of Pharmaceutical Sciences (1993) 82 (240-243)). December 15, 1993.

Full Text

HEIT, MC, WILLIAMS, PL, JAYES, FL, CHANG, SK, and RIVIERE, JE. "TRANSDERMAL IONTOPHORETIC PEPTIDE DELIVERY - INVITRO AND INVIVO STUDIES WITH LUTEINIZING-HORMONE-RELEASING HORMONE (VOL 82, PG 240, 1993)." JOURNAL OF PHARMACEUTICAL SCIENCES 82, no. 5 (May 1993): U554-U558.

Scholars@Duke

Heit, MC, Williams, PL, Jayes, FL, Chang, SK, and Riviere, JE. "Transdermal iontophoretic peptide delivery: in vitro and in vivo studies with luteinizing hormone releasing hormone." J Pharm Sci 82, no. 5 (May 1993): 240-243.

Scholars@Duke

HEIT, MC, WILLIAMS, PL, JAYES, FL, CHANG, SK, and RIVIERE, JE. "TRANSDERMAL LONTOPHORETIC PEPTIDE DELIVERY - INVITRO AND INVIVO STUDIES WITH LUTEINIZING-HORMONE-RELEASING HORMONE." JOURNAL OF PHARMACEUTICAL SCIENCES 82, no. 3 (March 1993): 240-243.

Full Text

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