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Liping Feng, MD

Property title
Assistant Professor of Obstetrics and Gynecology
Campus Mail: 303 Research Drive, 246 Sands, Durham, NC 27710
Phone: (919) 613-1459
Email: feng0007@mc.duke.edu

My research has focused on understanding the mechanisms of pregnancy complications associated with infection and maternal chemical exposures. These works are translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of adverse birth outcomes.

Liping Feng, MD, devotes her entire career to improving pregnancy outcomes through innovative research. Dr. Feng conducts both basic science/laboratory research, as well as participates in clinical studies. Her laboratory has focused on understanding the mechanisms of preterm birth, which is an important cause of perinatal and neonates’ mortality and morbidity. Currently, she has three lines of investigation focused on the roles of inflammation/infection, genetic variation, and environmental exposure in pregnancy complications, such as preterm birth and preeclampsia. This work is translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of pregnancy complications.

In addition, Dr. Feng has established an international collaboration in Global Women’s Health. She has recently affiliated with the Duke Global Health Institute (DGHI) and participates in a DGHI research. She has an interest in DGHI education, and service or policy initiatives, including mentoring and teaching graduate and professional students on fieldwork and research.

Education and Training

  • M.S., Chinese Center for Disease Control and Prevention (China), 2000
  • M.D., Harbin Medical University (China), 1997

Research

My research has focused on understanding the mechanisms of pregnancy complications associated with infection and maternal chemical exposures. These works are translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of adverse birth outcomes.

Liping Feng, MD, devotes her entire career to improving pregnancy outcomes through innovative research. Dr. Feng conducts both basic science/laboratory research, as well as participates in clinical studies. Her laboratory has focused on understanding the mechanisms of preterm birth, which is an important cause of perinatal and neonates’ mortality and morbidity. Currently, she has three lines of investigation focused on the roles of inflammation/infection, genetic variation, and environmental exposure in pregnancy complications, such as preterm birth and preeclampsia. This work is translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of pregnancy complications.

In addition, Dr. Feng has established an international collaboration in Global Women’s Health. She has recently affiliated with the Duke Global Health Institute (DGHI) and participates in a DGHI research. She has an interest in DGHI education, and service or policy initiatives, including mentoring and teaching graduate and professional students on fieldwork and research.

Projects

  • Understanding chemical exposure of PFBS during pregnancy and birth outcomes using in vitro and in vivo models. Using these models established in my lab, we could also test other environmental exposures

  • Investigating the impact of E-waste recycling and birth outcomes in China (Global health)

  • Building a novel in vitro placental model (collaboration with BME) to explore the mechanisms of ZIKA virus in utero transmission

  • Determine the roles of an understudied bacteria, Ureaplasma, in pregnancy

Publications

Feng, L, Antonia, A, Murtha, A, and Ko, D. "Racial Disparity in Ureaplasma Parvum Induced Inflammatory Responses." 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI). Orlando, FL. March 15, 2017 - March 18, 2017.: SAGE PUBLICATIONS INC, March 1, 2017.

Scholars@Duke

Feng, L, Antonia, A, Murtha, A, and Ko, D. "Racial Disparity in Ureaplasma Parvum Induced Inflammatory Responses." 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI). Orlando, FL. March 15, 2017 - March 18, 2017.: SAGE PUBLICATIONS INC, March 1, 2017.

Scholars@Duke

Feng, L, Jayes, FL, Johnson, LNC, Schomberg, DW, and Leppert, PC. "Biochemical Pathways and Myometrial Cell Differentiation Leading to Nodule Formation Containing Collagen and Fibronectin." Current protein & peptide science 18, no. 2 (January 2017): 155-166.

Full Text

Meng, Y, Murtha, AP, and Feng, L. "Progesterone, Inflammatory Cytokine (TNF-α), and Oxidative Stress (H2O2) Regulate Progesterone Receptor Membrane Component 1 Expression in Fetal Membrane Cells." Reproductive sciences (Thousand Oaks, Calif.) 23, no. 9 (September 2016): 1168-1178.

Full Text

Potts, LC, Feng, L, Seed, PC, Jayes, FL, Kuchibhatla, M, Antczak, B, Nazzal, MK, and Murtha, AP. "Inflammatory Response of Human Gestational Membranes to Ureaplasma parvum Using a Novel Dual-Chamber Tissue Explant System." Biology of reproduction 94, no. 5 (May 2016): 119-.

Full Text

Feng, L, Desravine, N, Nazzal, M, Pryor, K, and Murtha, A. "Characterization of Progesterone Receptor Membrane Component 1 in Peripheral Blood Mononuclear Cells and Plasma During Pregnancy." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016.

Scholars@Duke

Feng, L, Desravine, N, Nazzal, M, Pryor, K, and Murtha, A. "Characterization of Progesterone Receptor Membrane Component 1 in Peripheral Blood Mononuclear Cells and Plasma During Pregnancy." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016.

Scholars@Duke

Kim, E, Allen, TK, Feng, L, Nazzal, MK, and Murtha, AP. "The Effect of Cytokines on Neutrophil Gelatinase-Associated Lipocalin (NGAL) mRNA Expression in a Cytotrophoblast Cell Line." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016.

Scholars@Duke

Kim, E, Allen, TK, Feng, L, Nazzal, MK, and Murtha, AP. "The Effect of Cytokines on Neutrophil Gelatinase-Associated Lipocalin (NGAL) mRNA Expression in a Cytotrophoblast Cell Line." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016.

Scholars@Duke

Allen, T, Nazzal, M, Feng, L, Buhimschi, I, and Murtha, A. "The Role of PGRMC1 in Cytokine Induced MMP1, COX-2 and PGE(2) Expression in Amnion Mesenchymal Cells." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016.

Scholars@Duke

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