Helfand, Brian T., Victor P. Andreev, Nazema Y. Siddiqui, Gang Liu, Bradley A. Erickson, Margaret E. Helmuth, Susan K. Lutgendorf, H Henry Lai, Ziya Kirkali, and Ziya LURN Study Group. “A Novel Proteomics Approach to Identify Serum and Urinary Biomarkers and Pathways that Associate with Lower Urinary Tract Symptoms in Men and Women: Pilot Results of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Study..” Urology, March 25, 2019. https://doi.org/10.1016/j.urology.2019.03.014.
Nazema Yusuf Siddiqui, MD
Research on pelvic floor disorders. Specific interests include: 1) pathophysiology of overactive bladder with particular emphasis on epigenetic mechanisms; and 2) studying the urinary microbiome with aging and in women with recurrent urinary tract infection. Additional interests include clinical outcomes research after surgery for prolapse and other pelvic floor disorders.
Education and Training
- Fellow, Female Pelvic Medicine & Reconstructive Surgery, Obstetrics & Gynecology, Duke University School of Medicine, 2007 - 2010
- Residency, Ob/Gyn, MetroHealth Medical Center, Cleveland Clinic, 2002 - 2006
- M.H.S.C.R., Duke University School of Medicine, 2010
- M.D., University of Michigan at Ann Arbor, 2001
Research on pelvic floor disorders. Specific interests include the study of overactive bladder/urinary incontinence. Additional interests include studying the pathophysiology of bladder pain syndromes, and clinical outcomes research after surgery for prolapse and other pelvic floor disorders.
Selected Grants and Awards
- Effects of Aging and the Urinary Microbiome on Recurrent Urinary Tract Infections
- Duke University Medical Center (DUMC) Pelvic Floor Disorders Network (PFDN) Clinical Site
- Epigenomics in insulin resistance associated overactive bladder
- Fundamentals of Robotic Surgery: Curriculum and Technical Validation Skills
- Sexual Function in Patients and Partners after Surgery for Pelvic Organ Prolapse
Komesu, Yuko M., Holly E. Richter, Benjamin Carper, Darrell L. Dinwiddie, Emily S. Lukacz, Nazema Y. Siddiqui, Vivian W. Sung, et al. “The urinary microbiome in women with mixed urinary incontinence compared to similarly aged controls..” Int Urogynecol J 29, no. 12 (December 2018): 1785–95. https://doi.org/10.1007/s00192-018-3683-6.
Cameron, Anne P., Abigail R. Smith, H Henry Lai, Catherine S. Bradley, Alice B. Liu, Robert M. Merion, Brenda W. Gillespie, et al. “Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence..” Neurourol Urodyn 37, no. 8 (November 2018): 2586–96. https://doi.org/10.1002/nau.23587.
Askew, Amy L., Anthony G. Visco, Alison C. Weidner, Tracy Truong, Nazema Y. Siddiqui, and Megan S. Bradley. “Does Mesh Weight Affect Time to Failure After Robotic-Assisted Laparoscopic Sacrocolpopexy?.” Female Pelvic Med Reconstr Surg, October 12, 2018. https://doi.org/10.1097/SPV.0000000000000632.
Siddiqui, Nazema Y., Jonathan B. Wiseman, David Cella, Catherine S. Bradley, H Henry Lai, Margaret E. Helmuth, Abigail R. Smith, et al. “Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence..” J Urol 200, no. 4 (October 2018): 848–55. https://doi.org/10.1016/j.juro.2018.04.076.
Vaughan, Monique H., Nazema Y. Siddiqui, Laura K. Newcomb, Alison C. Weidner, Amie Kawasaki, Anthony G. Visco, and Megan S. Bradley. “Surgical Alteration of Genital Hiatus Size and Anatomic Failure After Vaginal Vault Suspension..” Obstet Gynecol 131, no. 6 (June 2018): 1137–44. https://doi.org/10.1097/AOG.0000000000002593.
Newcomb, Laura K., Megan S. Bradley, Tracy Truong, Michelle Tang, Bryan Comstock, Yi-Ju Li, Anthony G. Visco, and Nazema Y. Siddiqui. “Correlation of Virtual Reality Simulation and Dry Lab Robotic Technical Skills..” J Minim Invasive Gynecol 25, no. 4 (May 2018): 689–96. https://doi.org/10.1016/j.jmig.2017.11.006.
Bradley, Megan S., Emily E. Burke, Carole Grenier, Cindy L. Amundsen, Susan K. Murphy, and Nazema Y. Siddiqui. “A genome-scale DNA methylation study in women with interstitial cystitis/bladder pain syndrome..” Neurourol Urodyn 37, no. 4 (April 2018): 1485–93. https://doi.org/10.1002/nau.23489.
Cameron, Anne P., Christina Lewicky-Gaupp, Abigail R. Smith, Brian T. Helfand, John L. Gore, J Quentin Clemens, Claire C. Yang, et al. “Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study..” J Urol 199, no. 4 (April 2018): 1023–31. https://doi.org/10.1016/j.juro.2017.10.035.