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Nazema Yusuf Siddiqui, MD

Nazema Siddiqui, MD, MHSc
Associate Professor of Obstetrics and Gynecology
Campus Mail: 5324 McFarland Drive Suite 310, Box 3912, Durham, NC 27617
Phone: (919) 401-1000
Email: nazema.siddiqui@duke.edu

Research on pelvic floor disorders. Specific interests include: 1) pathophysiology of overactive bladder with particular emphasis on epigenetic mechanisms; and 2) studying the urinary microbiome with aging and in women with recurrent urinary tract infection. Additional interests include clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

Education and Training

  • Fellow, Female Pelvic Medicine & Reconstructive Surgery, Obstetrics & Gynecology, Duke University School of Medicine, 2007 - 2010
  • Residency, Ob/Gyn, MetroHealth Medical Center, Cleveland Clinic, 2002 - 2006
  • M.H.S.C.R., Duke University School of Medicine, 2010
  • M.D., University of Michigan at Ann Arbor, 2001

Research

Research on pelvic floor disorders. Specific interests include the study of overactive bladder/urinary incontinence. Additional interests include studying the pathophysiology of bladder pain syndromes, and clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

View Publications

Publications

Jelovsek, J Eric, Alayne D. Markland, William E. Whitehead, Matthew D. Barber, Diane K. Newman, Rebecca G. Rogers, Keisha Dyer, et al. “Controlling faecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomised clinical trial..” Lancet Gastroenterol Hepatol 4, no. 9 (September 2019): 698–710. https://doi.org/10.1016/S2468-1253(19)30193-1.

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Bickhaus, Jennifer A., Megan S. Bradley, Cindy L. Amundsen, Anthony G. Visco, Tracy Truong, Yi-Ju Li, and Nazema Y. Siddiqui. “Does a Recent Urinary Tract Infection Increase the Risk of Postprocedure Urinary Tract Infection After Onabotulinum Toxin A?.” Female Pelvic Med Reconstr Surg, July 8, 2019. https://doi.org/10.1097/SPV.0000000000000753.

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Helfand, Brian T., Victor P. Andreev, Nazema Y. Siddiqui, Gang Liu, Bradley A. Erickson, Margaret E. Helmuth, Susan K. Lutgendorf, H Henry Lai, Ziya Kirkali, and Ziya LURN Study Group. “A Novel Proteomics Approach to Identify Serum and Urinary Biomarkers and Pathways that Associate with Lower Urinary Tract Symptoms in Men and Women: Pilot Results of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Study..” Urology 129 (July 2019): 35–42. https://doi.org/10.1016/j.urology.2019.03.014.

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Meekins, A Rebecca, Susan K. Murphy, Carole Grenier, Zhiqing Huang, Megan S. Bradley, Cindy L. Amundsen, Jennifer Wu, and Nazema Y. Siddiqui. “Role of β-3 adrenergic receptor polymorphism in overactive bladder..” Neurourol Urodyn 38, no. 5 (June 2019): 1261–65. https://doi.org/10.1002/nau.24006.

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Siddiqui, Nazema Y., Brian T. Helfand, Victor P. Andreev, Joseph T. Kowalski, Megan S. Bradley, H Henry Lai, Mitchell B. Berger, et al. “Biomarkers Implicated in Lower Urinary Tract Symptoms: Systematic Review and Pathway Analyses..” J Urol, March 29, 2019. https://doi.org/10.1097/JU.0000000000000257.

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Vaughan, M. H., L. Giugale, N. Y. Siddiqui, and M. S. Bradley. “17: Impact of genital hiatus size on anatomic outcomes after mesh-augmented sacrospinous ligament fixation.” In American Journal of Obstetrics and Gynecology, 220:S700–701. Elsevier BV, 2019. https://doi.org/10.1016/j.ajog.2019.01.027.

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Komesu, Yuko M., Holly E. Richter, Benjamin Carper, Darrell L. Dinwiddie, Emily S. Lukacz, Nazema Y. Siddiqui, Vivian W. Sung, et al. “The urinary microbiome in women with mixed urinary incontinence compared to similarly aged controls..” Int Urogynecol J 29, no. 12 (December 2018): 1785–95. https://doi.org/10.1007/s00192-018-3683-6.

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Cameron, Anne P., Abigail R. Smith, H Henry Lai, Catherine S. Bradley, Alice B. Liu, Robert M. Merion, Brenda W. Gillespie, et al. “Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence..” Neurourol Urodyn 37, no. 8 (November 2018): 2586–96. https://doi.org/10.1002/nau.23587.

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Askew, Amy L., Anthony G. Visco, Alison C. Weidner, Tracy Truong, Nazema Y. Siddiqui, and Megan S. Bradley. “Does Mesh Weight Affect Time to Failure After Robotic-Assisted Laparoscopic Sacrocolpopexy?.” Female Pelvic Med Reconstr Surg, October 12, 2018. https://doi.org/10.1097/SPV.0000000000000632.

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Siddiqui, Nazema Y., Jonathan B. Wiseman, David Cella, Catherine S. Bradley, H Henry Lai, Margaret E. Helmuth, Abigail R. Smith, et al. “Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence..” J Urol 200, no. 4 (October 2018): 848–55. https://doi.org/10.1016/j.juro.2018.04.076.

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