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Nazema Yusuf Siddiqui, MD

Nazema Siddiqui, MD, MHSc
Associate Professor of Obstetrics and Gynecology
Campus Mail: 5324 McFarland Drive Suite 310, Box 3912, Durham, NC 27617
Phone: (919) 401-1000

Research on pelvic floor disorders. Specific interests include: 1) pathophysiology of overactive bladder with particular emphasis on epigenetic mechanisms; and 2) studying the urinary microbiome with aging and in women with recurrent urinary tract infection. Additional interests include clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

Education and Training

  • Fellow, Female Pelvic Medicine & Reconstructive Surgery, Obstetrics & Gynecology, Duke University School of Medicine, 2007 - 2010
  • Residency, Ob/Gyn, MetroHealth Medical Center, Cleveland Clinic, 2002 - 2006
  • M.H.S.C.R., Duke University School of Medicine, 2010
  • M.D., University of Michigan at Ann Arbor, 2001


Research on pelvic floor disorders. Specific interests include the study of overactive bladder/urinary incontinence. Additional interests include studying the pathophysiology of bladder pain syndromes, and clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

View Publications


Cameron, Anne P., Christina Lewicky-Gaupp, Abigail R. Smith, Brian T. Helfand, John L. Gore, J Quentin Clemens, Claire C. Yang, et al. “Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study..” J Urol 199, no. 4 (April 2018): 1023–31.

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Helmuth, Margaret E., Abigail R. Smith, Victor P. Andreev, Gang Liu, Gang LURN Study Group, H Henry Lai, Anne P. Cameron, and Nazema Y. Siddiqui. “Use of Euclidean length to measure urinary incontinence severity based on the lower urinary tract symptoms tool..” American Journal of Obstetrics and Gynecology 218, no. 3 (March 2018): 357–59.

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Arya, Lily A., Holly E. Richter, Eric Jelovsek, Marie Gantz, Sara Cichowski, Halina Zyczynski, Keisha Dyer, et al. “Metabolites and microbial composition of stool of women with fecal incontinence: Study design and methods..” Neurourol Urodyn 37, no. 2 (February 2018): 634–41.

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Komesu, Yuko M., Cindy L. Amundsen, Holly E. Richter, Stephen W. Erickson, Mary F. Ackenbom, Uduak U. Andy, Vivian W. Sung, et al. “Refractory urgency urinary incontinence treatment in women: impact of age on outcomes and complications..” Am J Obstet Gynecol 218, no. 1 (January 2018): 111.e1-111.e9.

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Meekins, A Rebecca, Nazema Y. Siddiqui, Cindy L. Amundsen, Maragatha Kuchibhatla, and Alexis A. Dieter. “Improving Postoperative Efficiency: An Algorithm for Expedited Void Trials After Urogynecologic Surgery..” South Med J 110, no. 12 (December 2017): 785–90.

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Weidner, Alison C., Matthew D. Barber, Alayne Markland, David D. Rahn, Yvonne Hsu, Elizabeth R. Mueller, Sharon Jakus-Waldman, et al. “Perioperative Behavioral Therapy and Pelvic Muscle Strengthening Do Not Enhance Quality of Life After Pelvic Surgery: Secondary Report of a Randomized Controlled Trial..” Phys Ther 97, no. 11 (November 1, 2017): 1075–83.

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Ju, Rujin, Nazema Siddiqui, Joanne Garrett, Liping Feng, and Michael Heit. “A validated translation of a survey for measuring incontinence knowledge in Chinese-speaking American immigrants..” Int Urogynecol J 28, no. 6 (June 2017): 851–56.

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Komesu, Yuko M., Holly E. Richter, Darrell L. Dinwiddie, Nazema Y. Siddiqui, Vivian W. Sung, Emily S. Lukacz, Beri Ridgeway, et al. “Methodology for a vaginal and urinary microbiome study in women with mixed urinary incontinence..” Int Urogynecol J 28, no. 5 (May 2017): 711–20.

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