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Nazema Yusuf Siddiqui, MD

Nazema Siddiqui, MD, MHSc
Associate Professor of Obstetrics and Gynecology
Campus Mail: 5324 McFarland Drive Suite 310, Box 3912, Durham, NC 27617
Phone: (919) 401-1000

Research on pelvic floor disorders. Specific interests include: 1) pathophysiology of overactive bladder with particular emphasis on epigenetic mechanisms; and 2) studying the urinary microbiome with aging and in women with recurrent urinary tract infection. Additional interests include clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

Education and Training

  • Fellow, Female Pelvic Medicine & Reconstructive Surgery, Obstetrics & Gynecology, Duke University School of Medicine, 2007 - 2010
  • Residency, Ob/Gyn, MetroHealth Medical Center, Cleveland Clinic, 2002 - 2006
  • M.H.S.C.R., Duke University School of Medicine, 2010
  • M.D., University of Michigan at Ann Arbor, 2001


Research on pelvic floor disorders. Specific interests include the study of overactive bladder/urinary incontinence. Additional interests include studying the pathophysiology of bladder pain syndromes, and clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

View Publications


Edenfield, Autumn L., Pamela J. Levin, Alexis A. Dieter, Jennifer M. Wu, and Nazema Y. Siddiqui. “Is postoperative bowel function related to posterior compartment prolapse repair?.” Female Pelvic Med Reconstr Surg 20, no. 2 (March 2014): 90–94.

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Zimmern, Philippe, Heather Litman, Charles Nager, Larry Sirls, Stephen R. Kraus, Kimberly Kenton, Tracey Wilson, et al. “Pre-operative urodynamics in women with stress urinary incontinence increases physician confidence, but does not improve outcomes..” Neurourol Urodyn 33, no. 3 (March 2014): 302–6.

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Jelovsek, J Eric, Kevin Chagin, Linda Brubaker, Rebecca G. Rogers, Holly E. Richter, Lily Arya, Matthew D. Barber, et al. “A model for predicting the risk of de novo stress urinary incontinence in women undergoing pelvic organ prolapse surgery..” Obstet Gynecol 123, no. 2 Pt 1 (February 2014): 279–87.

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Dieter, Alexis A., Cindy L. Amundsen, Autumn L. Edenfield, Amie Kawasaki, Pamela J. Levin, Anthony G. Visco, and Nazema Y. Siddiqui. “Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial..” Obstet Gynecol 123, no. 1 (January 2014): 96–103.

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Kawasaki, Amie, John P. Judd, Nazema Y. Siddiqui, Jennifer M. Wu, and Cindy L. Amundsen. “Impact of staged InterStim implantation on the postoperative activities of daily living and pain..” Int Urogynecol J 24, no. 7 (July 2013): 1205–13.

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Kawasaki, Amie, Elizabeth G. Corey, Robin A. Laskey, Alison C. Weidner, Nazema Y. Siddiqui, and Jennifer M. Wu. “Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy..” J Reprod Med 58, no. 5–6 (May 2013): 195–99.


Kawasaki, Amie, Autumn L. Edenfield, Anthony G. Visco, Jennifer M. Wu, Daniel Westreich, and Nazema Y. Siddiqui. “Comparing the risk of urethrolysis for the treatment of voiding dysfunction between two retropubic mesh slings: a case-control study..” Int Urogynecol J 24, no. 4 (April 2013): 589–94.

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Matteson, Kristen A., David D. Rahn, Thomas L. Wheeler, Elizabeth Casiano, Nazema Y. Siddiqui, Heidi S. Harvie, Mamta M. Mamik, Ethan M. Balk, Vivian W. Sung, and Vivian W. Society of Gynecologic Surgeons Systematic Review Group. “Nonsurgical management of heavy menstrual bleeding: a systematic review..” Obstet Gynecol 121, no. 3 (March 2013): 632–43.

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