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Robert Phillips Heine, MD

Property title
Professor of Obstetrics and Gynecology
Campus Mail: 2608 Erwin Road, Suite 200, Durham, NC 27705
Phone: (919) 668-0843

Dr. R. Phillips Heine is a Professor of Obstetrics & Gynecology and Pediatrics at Duke University Medical Center in Durham, NC. He currently serves as the Director of the Division of Maternal-Fetal Medicine, Vice Chair for Administration Affairs, and Medical Director for the Women’s Clinical Services Unit (CSU) in the Duke University Health System.

Dr. Heine completed his clinical training in Obstetrics and Gynecology at the University of North Carolina during which time he developed an academic interest regarding infection and its role in women’s reproductive health and specifically adverse pregnancy outcome. He subsequently completed a Sexually Transmitted Diseases research fellowship in the laboratories of Fred Sparling and Priscilla Wyrick at the University of North Carolina and went on to complete a Maternal-Fetal Medicine fellowship at the University of Colorado. After fellowship Dr. Heine became a faculty member at the University of Pittsburgh and an investigator at the Magee Women’s Research Institute. During this time he served as Resident Research Coordinator and Associate MFM fellowship director prior to his move to Duke University.

His current clinical and research interests focus on the role of infection and inflammation in preterm birth and other adverse pregnancy outcomes. He also has a specific interest in the use of immunizations in pregnancy for both the prevention of disease in the mother and the newborn. 

Education and Training

  • Fellow, Obstetrics & Gynecology, University of Colorado at Boulder, 1991 - 1993
  • Fellow, Obstetrics & Gynecology, North Carolina Memorial Hospital, 1990 - 1991
  • Resident, Obstetrics & Gynecology, North Carolina Memorial Hospital, 1986 - 1990
  • M.D., Texas Tech University of Health Science Nursing, 1986
Vice Chair Discipline: 


Canzoneri, BJ, Ellestad, SC, Brancazio, LR, Evans, AK, Grotegut, CA, Fitzpatrick, B, Reddick, K, Beiswenger, TR, Small, M, Boyd, BK, and Heine, RP. "P38.03: Prenatal diagnosis of an obstructing enterogenous cyst." Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 32, no. 3 (August 2008): 442-. (Academic Article)


Ellestad, SC, Swamy, GK, Sinclair, T, James, AH, Heine, RP, and Murtha, AP. "Preterm premature rupture of membrane management--inpatient versus outpatient: a retrospective review." Am J Perinatol 25, no. 1 (January 2008): 69-73.

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Pollak, KI, Oncken, CA, Lipkus, IM, Lyna, P, Swamy, GK, Pletsch, PK, Peterson, BL, Heine, RP, Brouwer, RJN, Fish, L, and Myers, ER. "Nicotine replacement and behavioral therapy for smoking cessation in pregnancy." Am J Prev Med 33, no. 4 (October 2007): 297-305.

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Simhan, HN, Anderson, BL, Krohn, MA, Heine, RP, Martinez de Tejada, B, Landers, DV, and Hillier, SL. "Host immune consequences of asymptomatic Trichomonas vaginalis infection in pregnancy." Am J Obstet Gynecol 196, no. 1 (January 2007): 59.e1-59.e5.

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Murtha, AP, Sinclair, T, Hauser, ER, Swamy, GK, Herbert, WNP, and Heine, RP. "Maternal serum cytokines in preterm premature rupture of membranes." Obstet Gynecol 109, no. 1 (January 2007): 121-127.

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Heine, RP, and Paglia, MJ. "Chlamydial Infection." (December 1, 2006): 103-111. (Chapter)

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Heine, RP, and Paglia, MJ. "Gonorrhea." (December 1, 2006): 97-102. (Chapter)

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Heine, RP, and Paglia, MJ. "HIV Infection." (December 1, 2006): 112-120. (Chapter)

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Heine, RP, and Paglia, MJ. "Syphilis." (December 1, 2006): 90-96. (Chapter)

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Murtha, AP, Nieves, A, Hauser, ER, Swamy, GK, Yonish, BA, Sinclair, TR, and Heine, RP. "Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth." Am J Obstet Gynecol 195, no. 5 (November 2006): 1249-1253.

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