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Robert Phillips Heine, MD

Property title
Professor of Obstetrics and Gynecology
Campus Mail: 2608 Erwin Road, Suite 200, Durham, NC 27705
Phone: (919) 668-0843

Dr. R. Phillips Heine is a Professor of Obstetrics & Gynecology and Pediatrics at Duke University Medical Center in Durham, NC. He currently serves as the Director of the Division of Maternal-Fetal Medicine, Vice Chair for Administration Affairs, and Medical Director for the Women’s Clinical Services Unit (CSU) in the Duke University Health System.

Dr. Heine completed his clinical training in Obstetrics and Gynecology at the University of North Carolina during which time he developed an academic interest regarding infection and its role in women’s reproductive health and specifically adverse pregnancy outcome. He subsequently completed a Sexually Transmitted Diseases research fellowship in the laboratories of Fred Sparling and Priscilla Wyrick at the University of North Carolina and went on to complete a Maternal-Fetal Medicine fellowship at the University of Colorado. After fellowship Dr. Heine became a faculty member at the University of Pittsburgh and an investigator at the Magee Women’s Research Institute. During this time he served as Resident Research Coordinator and Associate MFM fellowship director prior to his move to Duke University.

His current clinical and research interests focus on the role of infection and inflammation in preterm birth and other adverse pregnancy outcomes. He also has a specific interest in the use of immunizations in pregnancy for both the prevention of disease in the mother and the newborn. 

Education and Training

  • Fellow, Obstetrics & Gynecology, University of Colorado at Boulder, 1991 - 1993
  • Fellow, Obstetrics & Gynecology, North Carolina Memorial Hospital, 1990 - 1991
  • Resident, Obstetrics & Gynecology, North Carolina Memorial Hospital, 1986 - 1990
  • M.D., Texas Tech University of Health Science Nursing, 1986
Vice Chair Discipline: 


Murtha, AP, Sinclair, T, Hauser, ER, Swamy, GK, Herbert, WNP, and Heine, RP. "Maternal serum cytokines in preterm premature rupture of membranes." Obstetrics and Gynecology 109, no. 1 (January 2007): 121-127.

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Heine, RP, and Paglia, MJ. "Chlamydial Infection." (December 1, 2006): 103-111. (Chapter)

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Heine, RP, and Paglia, MJ. "Gonorrhea." (December 1, 2006): 97-102. (Chapter)

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Heine, RP, and Paglia, MJ. "HIV Infection." (December 1, 2006): 112-120. (Chapter)

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Heine, RP, and Paglia, MJ. "Syphilis." (December 1, 2006): 90-96. (Chapter)

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Murtha, AP, Nieves, A, Hauser, ER, Swamy, GK, Yonish, BA, Sinclair, TR, and Heine, RP. "Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth." American Journal of Obstetrics and Gynecology 195, no. 5 (November 2006): 1249-1253.

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Mills, AA, Yonish, B, Feng, L, Schomberg, DW, Heine, RP, and Murtha, AP. "Characterization of progesterone receptor isoform expression in fetal membranes." Am J Obstet Gynecol 195, no. 4 (October 2006): 998-1003.

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Swamy, GK, Simhan, HN, Gammill, HS, and Heine, RP. "Clinical utility of fetal fibronectin for predicting preterm birth." The Journal of Reproductive Medicine 50, no. 11 (November 2005): 851-856.


Sutkin, G, Krohn, MA, Heine, RP, and Sweet, RL. "Antibiotic prophylaxis and non-group B streptococcal neonatal sepsis." Obstet Gynecol 105, no. 3 (March 2005): 581-586.

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Simhan, H, Krohn, M, and Heine, RP. "Obstetric rectal injury: risk factors and the role of physician experience." The Journal of Maternal Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 16, no. 5 (November 2004): 271-274.

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