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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 701 W. Main Street, Suite 510, Room 5140, Durham, NC 27701
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Schechter, Julia, Elizabeth K. Do, Junfeng Jim Zhang, Cathrine Hoyo, Susan K. Murphy, Scott H. Kollins, and Bernard Fuemmeler. “Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms.” Nicotine Tob Res 22, no. 1 (January 27, 2020): 40–47. https://doi.org/10.1093/ntr/nty267.

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Yang, Wen-Hsuan, Zhiqing Huang, Jianli Wu, Chien-Kuang C. Ding, Susan K. Murphy, and Jen-Tsan Chi. “A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer.” Mol Cancer Res 18, no. 1 (January 2020): 79–90. https://doi.org/10.1158/1541-7786.MCR-19-0691.

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Schrott, Rose, Kelly Acharya, Nilda Itchon-Ramos, Andrew B. Hawkey, Erica Pippen, John T. Mitchell, Scott H. Kollins, Edward D. Levin, and Susan K. Murphy. “Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm.” Epigenetics 15, no. 1–2 (January 2020): 161–73. https://doi.org/10.1080/15592294.2019.1656158.

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Xue, Hong, Rachel L. Maguire, Jin Liu, Scott H. Kollins, Susan K. Murphy, Cathrine Hoyo, and Bernard F. Fuemmeler. “Snacking frequency and dietary intake in toddlers and preschool children.” Appetite 142 (November 1, 2019): 104369. https://doi.org/10.1016/j.appet.2019.104369.

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Yamanoi, Koji, Tsukasa Baba, Kaoru Abiko, Junzo Hamanishi, Ken Yamaguchi, Ryusuke Murakami, Mana Taki, et al. “Acquisition of a side population fraction augments malignant phenotype in ovarian cancer.” Sci Rep 9, no. 1 (October 2, 2019): 14215. https://doi.org/10.1038/s41598-019-50794-w.

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Sikdar, Sinjini, Roby Joehanes, Bonnie R. Joubert, Cheng-Jian Xu, Marta Vives-Usano, Faisal I. Rezwan, Janine F. Felix, et al. “Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.” Epigenomics 11, no. 13 (October 2019): 1487–1500. https://doi.org/10.2217/epi-2019-0066.

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House, John S., Jonathan Hall, Sarah S. Park, Antonio Planchart, Eric Money, Rachel L. Maguire, Zhiqing Huang, et al. “Cadmium exposure and MEG3 methylation differences between Whites and African Americans in the NEST Cohort.” Environ Epigenet 5, no. 3 (July 2019): dvz014. https://doi.org/10.1093/eep/dvz014.

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Hansen, Landon J., Ran Sun, Rui Yang, Simranjit X. Singh, Lee H. Chen, Christopher J. Pirozzi, Casey J. Moure, et al. “MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation.” Cancer Res 79, no. 13 (July 1, 2019): 3383–94. https://doi.org/10.1158/0008-5472.CAN-18-1010.

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Hawkey, Andrew B., Hannah White, Erica Pippen, Eva Greengrove, Amir H. Rezvani, Susan K. Murphy, and Edward D. Levin. “Paternal nicotine exposure in rats produces long-lasting neurobehavioral effects in the offspring.” Neurotoxicol Teratol 74 (July 2019): 106808. https://doi.org/10.1016/j.ntt.2019.05.001.

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Levin, Edward D., Andrew B. Hawkey, Brandon J. Hall, Marty Cauley, Susan Slade, Elisa Yazdani, Bruny Kenou, et al. “Paternal THC exposure in rats causes long-lasting neurobehavioral effects in the offspring.” Neurotoxicol Teratol 74 (July 2019): 106806. https://doi.org/10.1016/j.ntt.2019.04.003.

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