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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Moylan, Cynthia A., Carole Grenier, Jeongeun Hyun, Kuo Du, Ricardo Henao, Manal F. Abdelmalek, Susan K. Murphy, and Anna Mae Diehl. “DYSREGULATED DNA METHYLATION OF FGFR2, CASP1, AND BCAT1 ASSOCIATES WITH NONALCOHOLIC FATTY LIVER DISEASE SEVERITY AND CAN BE IDENTIFIED IN PERIPHERAL BLOOD.” In Gastroenterology, 156:S1360–61. W B SAUNDERS CO-ELSEVIER INC, 2019.

Scholars@Duke

Chawla, Devika, Bernard Fuemmeler, Sara E. Benjamin-Neelon, Cathrine Hoyo, Susan Murphy, and Julie L. Daniels. “Early prenatal vitamin D concentrations and social-emotional development in infants..” J Matern Fetal Neonatal Med 32, no. 9 (May 2019): 1441–48. https://doi.org/10.1080/14767058.2017.1408065.

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Küpers, Leanne K., Claire Monnereau, Gemma C. Sharp, Paul Yousefi, Lucas A. Salas, Akram Ghantous, Christian M. Page, et al. “Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight..” Nat Commun 10, no. 1 (April 23, 2019). https://doi.org/10.1038/s41467-019-09671-3.

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Martin, Chantel L., Dereje Jima, Gemma C. Sharp, Lauren E. McCullough, Sarah S. Park, Kymberly M. Gowdy, David Skaar, et al. “Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study..” Epigenetics 14, no. 4 (April 2019): 325–40. https://doi.org/10.1080/15592294.2019.1581594.

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Tagliafierro, Lidia, Ekaterina Ilich, Malik Moncalvo, Jeffrey Gu, Ahila Sriskanda, Carole Grenier, Susan K. Murphy, Ornit Chiba-Falek, and Boris Kantor. “Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models..” J Vis Exp, no. 145 (March 29, 2019). https://doi.org/10.3791/59241.

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Acharya, Kelly S., Rose Schrott, Edward Levin, and Susan K. Murphy. “Epigenetic Alterations in Cytochrome P450 Oxidoreductase (Por) in Sperm Exposed to Tetrahydrocannabinol (THC)..” In Reproductive Sciences, 26:92A-92A. SAGE PUBLICATIONS INC, 2019.

Scholars@Duke

Fuemmeler, Bernard F., Nancy Zucker, Yaou Sheng, Carmen E. Sanchez, Rachel Maguire, Susan K. Murphy, Scott H. Kollins, and Cathrine Hoyo. “Pre-Pregnancy Weight and Symptoms of Attention Deficit Hyperactivity Disorder and Executive Functioning Behaviors in Preschool Children..” Int J Environ Res Public Health 16, no. 4 (February 25, 2019). https://doi.org/10.3390/ijerph16040667.

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Do, E. K., N. L. Zucker, Z. Y. Huang, J. C. Schechter, S. H. Kollins, R. L. Maguire, S. K. Murphy, C. Hoyo, and B. F. Fuemmeler. “Associations between imprinted gene differentially methylated regions, appetitive traits and body mass index in children..” Pediatr Obes 14, no. 2 (February 2019). https://doi.org/10.1111/ijpo.12454.

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Sorrow, P., R. Maguire, S. K. Murphy, S. M. Belcher, and C. Hoyo. “Elevated metabolites of acetaminophen in cord blood of children with obesity..” Pediatr Obes 14, no. 1 (January 2019). https://doi.org/10.1111/ijpo.12465.

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Schechter, Julia, Elizabeth K. Do, Junfeng Jim Zhang, Cathrine Hoyo, Susan K. Murphy, Scott H. Kollins, and Bernard Fuemmeler. “Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms..” Nicotine Tob Res, December 24, 2018. https://doi.org/10.1093/ntr/nty267.

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