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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 226 B Wing LSRC, 450 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Vidal, AC, Overcash, F, Murphy, SK, Murtha, AP, Schildkraut, JM, Forman, MR, Demark-Wahnefried, W, Kurtzberg, J, Skaar, D, Jirtle, RL, and Hoyo, C. "Associations between birth and one year anthropometric measurements and IGF2 and IGF2R genetic variants in African American and Caucasian American infants." Journal of pediatric genetics 2, no. 3 (January 2013).

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Nye, MD, Hoyo, C, Huang, Z, Vidal, AC, Wang, F, Overcash, F, Smith, JS, Vasquez, B, Hernandez, B, Swai, B, Oneko, O, Mlay, P, Obure, J, Gammon, MD, Bartlett, JA, and Murphy, SK. "Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer." PLoS One 8, no. 2 (2013): e56325-.

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Bassil, CF, Huang, Z, and Murphy, SK. "Bisulfite pyrosequencing." Methods Mol Biol 1049 (2013): 95-107.

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Huang, Z, Bassil, CF, and Murphy, SK. "Bisulfite sequencing of cloned alleles." Methods Mol Biol 1049 (2013): 83-94.

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Liu, Y, Hoyo, C, Murphy, S, Huang, Z, Overcash, F, Thompson, J, Brown, H, and Murtha, AP. "DNA methylation at imprint regulatory regions in preterm birth and infection." American Journal of Obstetrics and Gynecology 208, no. 5 (2013): 395.e1-395.e7.

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Huang, Z, and Murphy, SK. "Increased Intragenic IGF2 Methylation is Associated with Repression of Insulator Activity and Elevated Expression in Serous Ovarian Carcinoma. (Published online)" Front Oncol 3 (2013): 131-.

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Murphy, SK, Bassil, CF, and Huang, Z. "Main principles and outcomes of DNA methylation analysis." Methods Mol Biol 1049 (2013): 67-74.

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Vidal, AC, Murtha, AP, Murphy, SK, Fortner, K, Overcash, F, Henry, N, Schildkraut, JM, Forman, MR, Demark-Wahnefried, W, Kurtzberg, J, Jirtle, R, and Hoyo, C. "Maternal BMI, IGF-I Levels, and Birth Weight in African American and White Infants." Int J Pediatr 2013 (2013): 191472-.

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Huang, Z, Bassil, CF, and Murphy, SK. "Methylation-specific PCR." Methods Mol Biol 1049 (2013): 75-82.

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Murphy, SK. "Prenatal sensitization of a postnatal trigger for metabolic disease." Journal of Clinical Investigation 123, no. 7 (2013): 2786-2788.

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