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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Sfakianos, GP, Iversen, ES, Whitaker, R, Akushevich, L, Schildkraut, JM, Murphy, SK, Marks, JR, and Berchuck, A. "Validation of ovarian cancer gene expression signatures for survival and subtype in formalin fixed paraffin embedded tissues." Gynecol Oncol 129, no. 1 (April 2013): 159-164.

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Murphy, SK, Nye, MD, and Hoyo, C. "Methylation at Imprinted Insulin-Like Growth Factor-2 (IGF2) Is Vulnerable to Lead Exposure in Human Embryonic Kidney Cells." March 2013.

Scholars@Duke

Murphy, SK, and Hollingsworth, JW. "Stress: a possible link between genetics, epigenetics, and childhood asthma." American Journal of Respiratory and Critical Care Medicine 187, no. 6 (March 2013): 563-564.

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Soubry, A, Schildkraut, JM, Murtha, A, Wang, F, Huang, Z, Bernal, A, Kurtzberg, J, Jirtle, RL, Murphy, SK, and Hoyo, C. "Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort." Bmc Medicine 11 (February 6, 2013): 29-null.

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Vidal, AC, Murphy, SK, Murtha, AP, Schildkraut, JM, Soubry, A, Huang, Z, Neelon, SEB, Fuemmeler, B, Iversen, E, Wang, F, Kurtzberg, J, Jirtle, RL, and Hoyo, C. "Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring." International Journal of Obesity 37, no. 7 (2013): 907-913.

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Vidal, AC, Overcash, F, Murphy, SK, Murtha, AP, Schildkraut, JM, Forman, MR, Demark-Wahnefried, W, Kurtzberg, J, Skaar, D, Jirtle, RL, and Hoyo, C. "Associations between birth and one year anthropometric measurements and IGF2 and IGF2R genetic variants in African American and Caucasian American infants." Journal of Pediatric Genetics 2, no. 3 (January 2013).

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Nye, MD, Hoyo, C, Huang, Z, Vidal, AC, Wang, F, Overcash, F, Smith, JS, Vasquez, B, Hernandez, B, Swai, B, Oneko, O, Mlay, P, Obure, J, Gammon, MD, Bartlett, JA, and Murphy, SK. "Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer." Plos One 8, no. 2 (January 2013): e56325-null.

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Bassil, CF, Huang, Z, and Murphy, SK. "Bisulfite pyrosequencing." Methods Mol Biol 1049 (2013): 95-107.

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Huang, Z, Bassil, CF, and Murphy, SK. "Bisulfite sequencing of cloned alleles." Methods Mol Biol 1049 (2013): 83-94.

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Liu, Y, Hoyo, C, Murphy, S, Huang, Z, Overcash, F, Thompson, J, Brown, H, and Murtha, AP. "DNA methylation at imprint regulatory regions in preterm birth and infection." American Journal of Obstetrics and Gynecology 208, no. 5 (2013): 395.e1-395.e7.

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