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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Matsumura, N, Huang, Z, Perry, T, Kroyer, D, Baba, T, Mori, S, Fujii, S, Berchuck, A, and Murphy, SK. "Methylation in ovarian cancer is related to poor prognosis and suppression of the transforming growth factor signaling pathway." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S104-S104.

Scholars@Duke

Bernardini, MQ, Lee, P, Baba, T, Whitaker, RS, Murphy, SK, and Berchuck, A. "Microarray analysis defines patterns of gene expression associated with mutation of TP53 in ovarian cancer." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S84-S84.

Scholars@Duke

Baba, T, Mori, S, Matsumura, N, Bernardini, M, Fujii, S, Berchuck, A, and Murphy, SK. "Microarray analysis identifies NSC668814 as a potentially active chemotherapeutic agent for platinum-resistant ovarian cancers with TP53 mutations." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S72-S72.

Scholars@Duke

Baba, T, Convery, PA, Matsumura, N, Whitaker, RS, Perry, T, Huang, Z, Mori, S, Kondoh, E, Bentley, RC, Fujii, S, Marks, JR, Berchuck, A, and Murphy, SK. "Stem cell marker CD133 (PROMININ-1) is epigenetically regulated in ovarian cancer." March 2008.

Scholars@Duke

Kondoh, E, Baba, T, Matsurnura, N, Fujii, S, Berchuck, A, and Murphy, SK. "Targeting dormant ovarian cancer cells." GYNECOLOGIC ONCOLOGY 108, no. 3 (March 2008): S13-S14.

Scholars@Duke

Baba, T, Convey, P, Matsumura, N, Whitaker, RS, Perry, T, Huang, Z, Mori, S, Kondoh, E, Bentley, RC, Fujii, S, Berchuck, A, Murphy, SK, and Marks, JR. "Stem cell marker CD133 (PROMININ-1) is epigenetically regulated in ovarian cancer." 2008.

Scholars@Duke

O'Sullivan, FM, Murphy, SK, Simel, LR, McCann, A, Callanan, JJ, and Nolan, CM. "Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation." Evol Dev 9, no. 6 (November 2007): 579-589.

Full Text

Baba, T, Mori, S, Matsumura, N, Kariya, M, Murphy, SK, Kondoh, E, Kusakari, T, Kuroda, H, Mandai, M, Higuchi, T, Takakura, K, Fukuda, MN, and Fujii, S. "Trophinin is a potent prognostic marker of ovarian cancer involved in platinum sensitivity." Biochem Biophys Res Commun 360, no. 2 (August 24, 2007): 363-369.

Full Text

Hempel, N, How, T, Dong, M, Murphy, SK, Fields, TA, and Blobe, GC. "Loss of betaglycan expression in ovarian cancer: role in motility and invasion." Cancer Research 67, no. 11 (June 2007): 5231-5238.

Full Text

Spillman, MA, Lacy, J, Murphy, SK, Whitaker, RS, Grace, L, Teaberry, V, Marks, JR, and Berchuck, A. "Regulation of the metastasis suppressor gene MKK4 in ovarian cancer." Gynecol Oncol 105, no. 2 (May 2007): 312-320.

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