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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards


Kantor, Boris, Lidia Tagliafierro, Jeffrey Gu, Madison E. Zamora, Ekaterina Ilich, Carole Grenier, Zhiqing Y. Huang, Susan Murphy, and Ornit Chiba-Falek. “Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD..” Mol Ther 26, no. 11 (November 7, 2018): 2638–49.

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Moylan, Cynthia A., Patricia A. Sorrow, Alisha Mavis, Mustafa Bashir, Dereje Jima, Rachel Maguire, Erol Bozdogan, et al. “Obesity and Nonalcoholic Fatty Liver Disease in Childhood Associate with Altered DNA Methylation in Early Life.” In Hepatology, 68:949A-950A. WILEY, 2018.


Gomih, Ayodele, Jennifer S. Smith, Kari E. North, Michael G. Hudgens, Wendy R. Brewster, Zhiqing Huang, David Skaar, et al. “DNA methylation of imprinted gene control regions in the regression of low-grade cervical lesions..” Int J Cancer 143, no. 3 (August 1, 2018): 552–60.

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Gao, Lu, Xiaochen Liu, Joshua Millstein, Kimberly D. Siegmund, Louis Dubeau, Rachel L. Maguire, Junfeng Jim Zhang, et al. “Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes..” Clin Epigenetics 10, no. 1 (July 20, 2018).

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Green, Adrian J., Cathrine Hoyo, Carolyn J. Mattingly, Yiwen Luo, Jung-Ying Tzeng, Susan K. Murphy, David B. Buchwalter, and Antonio Planchart. “Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study..” Int J Obes (Lond) 42, no. 7 (July 2018): 1285–95.

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Tindula, Gwen, Susan K. Murphy, Carole Grenier, Zhiqing Huang, Karen Huen, Maria Escudero-Fung, Asa Bradman, Brenda Eskenazi, Cathrine Hoyo, and Nina Holland. “DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure..” In Epigenomics, 10:1011–26, 2018.

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Dozmorov, Mikhail G., Staci D. Bilbo, Scott H. Kollins, Nancy Zucker, Elizabeth K. Do, Julia C. Schechter, Junfeng Jim Zhang, Susan K. Murphy, Cathrine Hoyo, and Bernard F. Fuemmeler. “Associations between maternal cytokine levels during gestation and measures of child cognitive abilities and executive functioning..” Brain Behav Immun 70 (May 2018): 390–97.

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Bradley, Megan S., Emily E. Burke, Carole Grenier, Cindy L. Amundsen, Susan K. Murphy, and Nazema Y. Siddiqui. “A genome-scale DNA methylation study in women with interstitial cystitis/bladder pain syndrome..” Neurourol Urodyn 37, no. 4 (April 2018): 1485–93.

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Benjamin Neelon, S. E., A. J. White, A. C. Vidal, J. M. Schildkraut, A. P. Murtha, S. K. Murphy, S. W. Kullman, and C. Hoyo. “Maternal vitamin D, DNA methylation at imprint regulatory regions and offspring weight at birth, 1 year and 3 years..” Int J Obes (Lond) 42, no. 4 (April 2018): 587–93.

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