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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 226 B Wing LSRC, 450 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Evans, HK, Wylie, AA, Murphy, SK, and Jirtle, RL. "NNATresides in a micro-imprinted domain on human chromosome 20q11.2." AMERICAN JOURNAL OF HUMAN GENETICS 69, no. 4 (October 2001): 346-346.

Scholars@Duke

Evans, HK, Wylie, AA, Murphy, SK, and Jirtle, RL. "The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2." Genomics 77, no. 1-2 (September 2001): 99-104.

Full Text

Keller, MA, Murphy, SK, and Parks, GD. "RNA replication from the simian virus 5 antigenomic promoter requires three sequence-dependent elements separated by sequence-independent spacer regions." J Virol 75, no. 8 (April 2001): 3993-3998.

Full Text

Murphy, SK, Wylie, AA, and Jirtle, RL. "Imprinting of PEG3, the human homologue of a mouse gene involved in nurturing behavior." Genomics 71, no. 1 (January 1, 2001): 110-117.

Full Text

Wylie, AA, Murphy, SK, Orton, TC, and Jirtle, RL. "Novel imprinted DLK1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation." Genome Res 10, no. 11 (November 2000): 1711-1718.

Scholars@Duke

Wylie, AA, Murphy, SK, Orton, TC, and Jirtle, RL. "Identification of a novel imprinted domain at human chromosome 14q32." AMERICAN JOURNAL OF HUMAN GENETICS 67, no. 4 (October 2000): 190-190.

Scholars@Duke

Murphy, SK, Wylie, AA, and Jirtle, RL. "Imprinting of PEG3, the human homolog of a gene involved in nurturing behaviour." AMERICAN JOURNAL OF HUMAN GENETICS 67, no. 4 (October 2000): 189-189.

Scholars@Duke

Murphy, SK, and Jirtle, RL. "Imprinted genes as potential genetic and epigenetic toxicologic targets." Environ Health Perspect 108 Suppl 1 (March 2000): 5-11. (Review)

Scholars@Duke

Murphy, SK, and Parks, GD. "RNA replication for the paramyxovirus simian virus 5 requires an internal repeated (CGNNNN) sequence motif." J Virol 73, no. 1 (January 1999): 805-809.

Scholars@Duke

Murphy, SK, Ito, Y, and Parks, GD. "A functional antigenomic promoter for the paramyxovirus simian virus 5 requires proper spacing between an essential internal segment and the 3' terminus." J Virol 72, no. 1 (January 1998): 10-19.

Scholars@Duke

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