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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Murphy, S. K., A. A. Wylie, and R. L. Jirtle. “Imprinting of PEG3, the human homologue of a mouse gene involved in nurturing behavior..” Genomics 71, no. 1 (January 2001): 110–17. https://doi.org/10.1006/geno.2000.6419.

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Wylie, A. A., S. K. Murphy, T. C. Orton, and R. L. Jirtle. “Novel imprinted DLK1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation..” Genome Res 10, no. 11 (November 2000): 1711–18. https://doi.org/10.1101/gr.161600.

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Wylie, A. A., S. K. Murphy, T. C. Orton, and R. L. Jirtle. “Identification of a novel imprinted domain at human chromosome 14q32..” American Journal of Human Genetics 67, no. 4 (October 1, 2000): 190–190.

Scholars@Duke

Murphy, S. K., A. A. Wylie, and R. L. Jirtle. “Imprinting of PEG3, the human homolog of a gene involved in nurturing behaviour..” American Journal of Human Genetics 67, no. 4 (October 1, 2000): 189–189.

Scholars@Duke

Murphy, S. K., and G. D. Parks. “RNA replication for the paramyxovirus simian virus 5 requires an internal repeated (CGNNNN) sequence motif..” J Virol 73, no. 1 (January 1999): 805–9.

Scholars@Duke

Murphy, S. K., Y. Ito, and G. D. Parks. “A functional antigenomic promoter for the paramyxovirus simian virus 5 requires proper spacing between an essential internal segment and the 3' terminus..” J Virol 72, no. 1 (January 1998): 10–19.

Scholars@Duke

Murphy, S. K., and G. D. Parks. “Genome nucleotide lengths that are divisible by six are not essential but enhance replication of defective interfering RNAs of the paramyxovirus simian virus 5..” Virology 232, no. 1 (May 26, 1997): 145–57. https://doi.org/10.1006/viro.1997.8530.

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Murphy, S. K., and J. D. Oliver. “Effects of temperature abuse on survival of Vibrio vulnificus in oysters..” Appl Environ Microbiol 58, no. 9 (September 1992): 2771–75.

Scholars@Duke

Bradley, Megan S., Marie-Helene Boudreau, Carole Grenier, Zhiqing Huang, Susan K. Murphy, and Nazema Y. Siddiqui. “Urine RNA Processing in a Clinical Setting: Comparison of 3 Protocols..” Female Pelvic Med Reconstr Surg 25, no. 3 (n.d.): 247–51. https://doi.org/10.1097/SPV.0000000000000525.

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