Skip to main content

Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Maguire, RL, Vidal, AC, Murphy, SK, and Hoyo, C. "Disparities in Cervical Cancer Incidence and Mortality: Can Epigenetics Contribute to Eliminating Disparities?." Advances in cancer research 133 (January 2017): 129-156. (Review)

Full Text

Gao, L, Millstein, J, Siegmund, KD, Dubeau, L, Maguire, R, Gilliland, FD, Murphy, SK, Hoyo, C, and Breton, CV. "Epigenetic regulation of AXL and risk of childhood asthma symptoms." Clinical Epigenetics 9 (January 2017): 121-null.

Full Text

Soubry, A, Hoyo, C, Butt, CM, Fieuws, S, Price, TM, Murphy, SK, and Stapleton, HM. "Human exposure to flame-retardants is associated with aberrant DNA methylation at imprinted genes in sperm." Environmental Epigenetics 3, no. 1 (January 2017): dvx003-null.

Full Text

Moylan, CA, Wegermann, KJ, Henao, RG, Murphy, SK, Diehl, AM, and Abdelmalek, MF. "BCAT1 Is Associated with Clinical Decompensation in Nonalcoholic Fatty Liver Disease: a Pilot Study." October 2016.

Scholars@Duke

Murphy, SK, Keyhan, S, Guo, L, Tomins, K, Taylor, M, Joglekar, R, Huang, Z, Grenier, C, Liao, Y, Massarsky, A, Soubry, A, Lea, A, Burke, EE, Cauley, M, Hall, BJ, Lucas, JE, Hoyo, C, Di Giulio, RT, Levin, ED, and Price, TM. "Environmental Influence on Preconceptional and Gestational DNA Methylation Profiles." September 2016.

Scholars@Duke

Moylan, CA, and Murphy, SK. "DNA Methylation: Basic Principles." In Medical Epigenetics, 11-31. July 1, 2016.

Full Text

Yamanoi, K, Matsumura, N, Murphy, SK, Baba, T, Abiko, K, Hamanishi, J, Yamaguchi, K, Koshiyama, M, Konishi, I, and Mandai, M. "Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer." Oncotarget 7, no. 30 (July 2016): 47620-47636.

Full Text

Schiöth, HB, Boström, A, Murphy, SK, Erhart, W, Hampe, J, Moylan, C, and Mwinyi, J. "A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease." BMC genomics 17 (June 14, 2016): 462-.

Full Text

Fuemmeler, BF, Wang, L, Iversen, ES, Maguire, R, Murphy, SK, and Hoyo, C. "Association between Prepregnancy Body Mass Index and Gestational Weight Gain with Size, Tempo, and Velocity of Infant Growth: Analysis of the Newborn Epigenetic Study Cohort." Childhood Obesity 12, no. 3 (June 2016): 210-218.

Full Text

Dewi, FN, Wood, CE, Willson, CJ, Register, TC, Lees, CJ, Howard, TD, Huang, Z, Murphy, SK, Tooze, JA, Chou, JW, Miller, LD, and Cline, JM. "Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques." Cancer Prevention Research (Philadelphia, Pa.) 9, no. 5 (May 2016): 385-395.

Full Text

Pages