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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Felix, Janine F., Bonnie R. Joubert, Andrea A. Baccarelli, Gemma C. Sharp, Catarina Almqvist, Isabella Annesi-Maesano, Hasan Arshad, et al. “Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium..” Int J Epidemiol 47, no. 1 (February 1, 2018): 22-23u. https://doi.org/10.1093/ije/dyx190.

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Schechter, Julia C., Bernard F. Fuemmeler, Cathrine Hoyo, Susan K. Murphy, Junfeng Jim Zhang, and Scott H. Kollins. “Impact of Smoking Ban on Passive Smoke Exposure in Pregnant Non-Smokers in the Southeastern United States..” Int J Environ Res Public Health 15, no. 1 (January 6, 2018). https://doi.org/10.3390/ijerph15010083.

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Wegermann, Kara, Ricardo Henao, Anna Mae Diehl, Susan K. Murphy, Manal F. Abdelmalek, and Cynthia A. Moylan. “Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study..” Plos One 13, no. 9 (2018). https://doi.org/10.1371/journal.pone.0204308.

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Murphy, Susan K., Nilda Itchon-Ramos, Zachary Visco, Zhiqing Huang, Carole Grenier, Rose Schrott, Kelly Acharya, et al. “Cannabinoid exposure and altered DNA methylation in rat and human sperm..” Epigenetics 13, no. 12 (2018): 1208–21. https://doi.org/10.1080/15592294.2018.1554521.

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Gonzalez-Nahm, Sarah, Michelle A. Mendez, Sara E. Benjamin-Neelon, Susan K. Murphy, Vijaya K. Hogan, Diane L. Rowley, and Cathrine Hoyo. “DNA methylation of imprinted genes at birth is associated with child weight status at birth, 1 year, and 3 years..” Clin Epigenetics 10 (2018). https://doi.org/10.1186/s13148-018-0521-0.

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House, John S., Michelle Mendez, Rachel L. Maguire, Sarah Gonzalez-Nahm, Zhiqing Huang, Julie Daniels, Susan K. Murphy, Bernard F. Fuemmeler, Fred A. Wright, and Cathrine Hoyo. “Periconceptional Maternal Mediterranean Diet Is Associated With Favorable Offspring Behaviors and Altered CpG Methylation of Imprinted Genes..” Frontiers in Cell and Developmental Biology 6 (January 2018). https://doi.org/10.3389/fcell.2018.00107.

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Kollins, Scott, Ed Levin, Tom Price, and Susan Murphy. “Delta-9-Tetrahydrocannabinol Exposure Alters Sperm Methylation Profiles: Concurrent Results From Humans and Rats.” In Neuropsychopharmacology, 42:S642–43. NATURE PUBLISHING GROUP, 2017.

Scholars@Duke

Sharp, Gemma C., Lucas A. Salas, Claire Monnereau, Catherine Allard, Paul Yousefi, Todd M. Everson, Jon Bohlin, et al. “Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium..” Hum Mol Genet 26, no. 20 (October 15, 2017): 4067–85. https://doi.org/10.1093/hmg/ddx290.

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Li, Xiaoyi, Cynthia A. Moylan, Susan S. Baker, Wensheng Liu, Robert D. Baker, Susan K. Murphy, Manal F. Abdelmalek, Ruixin Zhu, Anna Mae Diehl, and Lixin Zhu. “Altered liver methylome and transcriptome provide evidence for epigenetic contribution to NAFLD pathogenesis.” In Hepatology, 66:1071A-1072A. WILEY, 2017.

Scholars@Duke

Moylan, Cynthia A., Alisha M. Mavis, Mustafa R. Bashir, David Malik, Erol Bozdogan, Stephanie Buie, Cathrine Hoyo, Anna Mae Diehl, Susan K. Murphy, and Manal F. Abdelmalek. “Visceral and subcutaneous adipose tissue measurements associate with increased metabolic risk for NAFLD in pre-pubertal obese children.” In Hepatology, 66:665A-665A. WILEY, 2017.

Scholars@Duke

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