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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Mwinyi, Jessica, Adrian E. Boström, Claudia Pisanu, Susan K. Murphy, Wiebke Erhart, Clemens Schafmayer, Jochen Hampe, Cynthia Moylan, and Helgi B. Schiöth. “NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition..” Biochim Biophys Acta Mol Cell Biol Lipids 1862, no. 3 (March 2017): 314–23. https://doi.org/10.1016/j.bbalip.2016.12.005.

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Bradley, Megan S., Marie-Helene Boudreau, Carole Grenier, Zhiqing Huang, Susan Murphy, and Nazema Y. Siddiqui. “STANDARDIZATION OF RNA PROCESSING FROM URINE SEDIMENT IN A CLINICAL SETTING.” In Neurourology and Urodynamics, 36:S18–S18. WILEY-BLACKWELL, 2017.

Scholars@Duke

Bradley, Megan S., Emily Burke, Carole Grenier, Cindy L. Amundsen, Susan Murphy, and Nazema Y. Siddiqui. “URINARY METHYLATION PATTERNS IN WOMEN WITH INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME.” In Neurourology and Urodynamics, 36:S17–18. WILEY-BLACKWELL, 2017.

Scholars@Duke

Maguire, R. L., A. C. Vidal, S. K. Murphy, and C. Hoyo. “Disparities in Cervical Cancer Incidence and Mortality: Can Epigenetics Contribute to Eliminating Disparities?.” Adv Cancer Res 133 (2017): 129–56. https://doi.org/10.1016/bs.acr.2016.09.001.

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Gao, Lu, Joshua Millstein, Kimberly D. Siegmund, Louis Dubeau, Rachel Maguire, Frank D. Gilliland, Susan K. Murphy, Cathrine Hoyo, and Carrie V. Breton. “Epigenetic regulation of AXL and risk of childhood asthma symptoms..” Clin Epigenetics 9 (2017). https://doi.org/10.1186/s13148-017-0421-8.

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Soubry, Adelheid, Cathrine Hoyo, Craig M. Butt, Steffen Fieuws, Thomas M. Price, Susan K. Murphy, and Heather M. Stapleton. “Human exposure to flame-retardants is associated with aberrant DNA methylation at imprinted genes in sperm..” Environ Epigenet 3, no. 1 (January 2017). https://doi.org/10.1093/eep/dvx003.

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Moylan, Cynthia A., Kara J. Wegermann, Ricardo G. Henao, Susan K. Murphy, Anna Mae Diehl, and Manal F. Abdelmalek. “BCAT1 Is Associated with Clinical Decompensation in Nonalcoholic Fatty Liver Disease: a Pilot Study.” In American Journal of Gastroenterology, 111:S381–S381. Ovid Technologies (Wolters Kluwer Health), 2016. https://doi.org/10.14309/00000434-201610001-00871.

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Murphy, S. K., S. Keyhan, L. Guo, K. Tomins, M. Taylor, R. Joglekar, Z. Huang, et al. “Environmental Influence on Preconceptional and Gestational DNA Methylation Profiles..” In Environmental and Molecular Mutagenesis, 57:S39–S39. WILEY-BLACKWELL, 2016.

Scholars@Duke

Yamanoi, Koji, Noriomi Matsumura, Susan K. Murphy, Tsukasa Baba, Kaoru Abiko, Junzo Hamanishi, Ken Yamaguchi, Masafumi Koshiyama, Ikuo Konishi, and Masaki Mandai. “Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer..” Oncotarget 7, no. 30 (July 26, 2016): 47620–36. https://doi.org/10.18632/oncotarget.9951.

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