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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Huang, Z, Visco, Z, Sfakianos, G, Whitaker, R, Berchuck, A, and Murphy, SK. "Abstract 2236: Emergence of epigenetic regulation of tight junction genes in recurrent serous epithelial ovarian cancer." August 1, 2015.

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Vidal, AC, Semenova, V, Darrah, T, Vengosh, A, Huang, Z, King, K, Nye, MD, Fry, R, Skaar, D, Maguire, R, Murtha, A, Schildkraut, J, Murphy, S, and Hoyo, C. "Maternal cadmium, iron and zinc levels, DNA methylation and birth weight." Bmc Pharmacology & Toxicology 16 (July 15, 2015): 20-null.

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Taylor, MM, and Murphy, SK. "Systems Biology and the Epigenome." In Systems Biology in Toxicology and Environmental Health, 43-56. July 7, 2015.

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King, K, Murphy, S, and Hoyo, C. "Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status." Journal of epidemiology and community health 69, no. 7 (July 2015): 639-647.

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Baba, T, Kang, HS, Hosoe, Y, Kharma, B, Abiko, K, Matsumura, N, Hamanishi, J, Yamaguchi, K, Yoshioka, Y, Koshiyama, M, Mandai, M, Murphy, SK, and Konishi, I. "Menstrual cyclic change of metastin/GPR54 in endometrium." Medical Molecular Morphology 48, no. 2 (June 1, 2015): 76-84.

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Baba, T, Kang, HS, Hosoe, Y, Kharma, B, Abiko, K, Matsumura, N, Hamanishi, J, Yamaguchi, K, Yoshioka, Y, Koshiyama, M, Mandai, M, Murphy, SK, and Konishi, I. "Menstrual cyclic change of metastin/GPR54 in endometrium." Medical molecular morphology 48, no. 2 (June 2015): 76-84.

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Tang, X, Keenan, MM, Wu, J, Lin, C-A, Dubois, L, Thompson, JW, Freedland, SJ, Murphy, SK, and Chi, J-T. "Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesis." Plos Genetics 11, no. 4 (April 7, 2015): e1005158-null.

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Cobb, L, Whitaker, R, Hall, A, Broadwater, G, Murphy, S, Berchuck, A, and Gaillard, S. "Evaluation of ERRα expression and association with survival in advanced ovarian cancer." April 2015.

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Nye, MD, Hoyo, C, and Murphy, SK. "In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST." Toxicology in Vitro : an International Journal Published in Association With Bibra 29, no. 3 (April 2015): 544-550.

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Soubry, A, Murphy, SK, Wang, F, Huang, Z, Vidal, AC, Fuemmeler, BF, Kurtzberg, J, Murtha, A, Jirtle, RL, Schildkraut, JM, and Hoyo, C. "Newborns of obese parents have altered DNA methylation patterns at imprinted genes." International Journal of Obesity (2005) 39, no. 4 (April 2015): 650-657.

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