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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 226 B Wing LSRC, 450 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Kharma, B, Baba, T, Matsumura, N, Kang, HS, Hamanishi, J, Murakami, R, McConechy, MM, Leung, S, Yamaguchi, K, Hosoe, Y, Yoshioka, Y, Murphy, SK, Mandai, M, Hunstman, DG, and Konishi, I. "STAT1 drives tumor progression in serous papillary endometrial cancer." Cancer research 74, no. 22 (November 2014): 6519-6530.

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Stevens, EV, Whitaker, R, Guinet, A, Chang, C-Y, Grenier, C, Marks, J, McDonnell, DP, Murphy, SK, Berchuck, A, and Gaillard, S. "Abstract 4570: Role of ERRalpha in ovarian cancer." October 1, 2014.

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Kharma, B, Baba, T, Matsumura, N, Kang, HS, Murakami, R, Yamaguchi, K, Hamanishi, J, Mandai, M, Murphy, SK, and Konishi, I. "Abstract LB-123: Novel function of STAT1 pathway as a modulator of tumor progression in serous papillary endometrial cancer." October 1, 2014.

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Yamaguchi, K, Huang, Z, Matsumura, N, Mandai, M, Okamoto, T, Baba, T, Konishi, I, Berchuck, A, and Murphy, SK. "Epigenetic determinants of ovarian clear cell carcinoma biology." International Journal of Cancer 135, no. 3 (August 1, 2014): 585-597.

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Yamaguchi, K, Huang, Z, Matsumura, N, Mandai, M, Okamoto, T, Baba, T, Konishi, I, Berchuck, A, and Murphy, SK. "Epigenetic determinants of ovarian clear cell carcinoma biology." Int J Cancer 135, no. 3 (August 1, 2014): 585-597.

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Hoyo, C, Daltveit, AK, Iversen, E, Benjamin-Neelon, SE, Fuemmeler, B, Schildkraut, J, Murtha, AP, Overcash, F, Vidal, AC, Wang, F, Huang, Z, Kurtzberg, J, Seewaldt, V, Forman, M, Jirtle, RL, and Murphy, SK. "Erythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohort." Epigenetics 9, no. 8 (August 2014): 1120-1130.

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Vidal, AC, Smith, JS, Valea, F, Bentley, R, Gradison, M, Yarnall, KSH, Ford, A, Overcash, F, Grant, K, Murphy, SK, and Hoyo, C. "HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA." Cancer causes & control : CCC 25, no. 8 (August 2014): 1055-1062.

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Murphy, SK. "Obesity: Paternal obesity--a risk factor for autism?." Nature reviews. Endocrinology 10, no. 7 (July 2014): 389-390.

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Smeester, L, Yosim, AE, Nye, MD, Hoyo, C, Murphy, SK, and Fry, RC. "Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury." Genes 5, no. 2 (June 11, 2014): 477-496.

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Soubry, A, Hoyo, C, Jirtle, RL, and Murphy, SK. "A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line." BioEssays 36, no. 4 (April 1, 2014): 359-371.

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