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Rebecca A Previs, MD

Property title
Assistant Professor of Obstetrics and Gynecology
Campus Mail: Dept Of Obgyn, Box 3616, Durham, NC 27710
Phone: (919) 684-8111
Email: rebecca.previs@duke.edu

Education and Training

  • M.D., University of Virginia School of Medicine, 2009

Research

Research interests include early phase clinical trials, novel therapeutics, the microenvironment, and personalized medicine.  I am working on translating what we learn at the laboratory bench into better therapies for our patients.  I am interested in gaining a better understanding of the immune microenvironment to determine how cancer cells evade discovery by our own immune systems.

Publications

Huang, Y, Hu, W, Huang, J, Shen, F, Sun, Y, Ivan, C, Pradeep, S, Dood, R, Haemmerle, M, Jiang, D, Mangala, LS, Noh, K, Hansen, JM, Dalton, HJ, Previs, RA, Nagaraja, AS, McGuire, M, Jennings, NB, Broaddus, R, Coleman, RL, and Sood, AK. "Inhibiting nuclear phospho-progesterone receptor enhances antitumor activity of onapristone in uterine cancer." Molecular Cancer Therapeutics 17, no. 2 (February 1, 2018): 464-473.

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Previs, RA, Armaiz-Pena, GN, Ivan, C, Dalton, HJ, Rupaimoole, R, Hansen, JM, Lyons, Y, Huang, J, Haemmerle, M, Wagner, MJ, Gharpure, KM, Nagaraja, AS, Filant, J, McGuire, MH, Noh, K, Dorniak, PL, Linesch, SL, Mangala, LS, Pradeep, S, Wu, SY, and Sood, AK. "Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies." JNCI Journal of the National Cancer Institute 109, no. 7 (July 2017).

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Huang, Y, Lichtenberger, LM, Taylor, M, Bottsford-Miller, JN, Haemmerle, M, Wagner, MJ, Lyons, Y, Pradeep, S, Hu, W, Previs, RA, Hansen, JM, Fang, D, Dorniak, PL, Filant, J, Dial, EJ, Shen, F, Hatakeyama, H, and Sood, AK. "Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer." Molecular cancer therapeutics 15, no. 12 (December 2016): 2894-2904.

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Previs, RA, Sood, AK, Mills, GB, and Westin, SN. "The rise of genomic profiling in ovarian cancer." Expert review of molecular diagnostics 16, no. 12 (December 2016): 1337-1351. (Review)

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Highley, LL, Previs, RA, Dotters-Katz, SK, Brancazio, LR, and Grotegut, CA. "Cesarean delivery among women with prolonged labor induction." Journal of perinatal medicine 44, no. 7 (October 2016): 759-766.

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Whiting, N, Hu, J, Zacharias, NM, Lokesh, GLR, Volk, DE, Menter, DG, Rupaimoole, R, Previs, R, Sood, AK, and Bhattacharya, P. "Developing hyperpolarized silicon particles for in vivo MRI targeting of ovarian cancer." Journal of Medical Imaging 3, no. 3 (August 10, 2016): 036001-036001.

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Rupaimoole, R, Ivan, C, Yang, D, Gharpure, KM, Wu, SY, Pecot, CV, Previs, RA, Nagaraja, AS, Armaiz-Pena, GN, McGuire, M, Pradeep, S, Mangala, LS, Rodriguez-Aguayo, C, Huang, L, Bar-Eli, M, Zhang, W, Lopez-Berestein, G, Calin, GA, and Sood, AK. "Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression." Oncogene 35, no. 33 (August 2016): 4312-4320.

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Huang, J, Hu, W, Hu, L, Previs, RA, Dalton, HJ, Yang, X-Y, Sun, Y, McGuire, M, Rupaimoole, R, Nagaraja, AS, Kang, Y, Liu, T, Nick, AM, Jennings, NB, Coleman, RL, Jaffe, RB, and Sood, AK. "Dll4 Inhibition plus Aflibercept Markedly Reduces Ovarian Tumor Growth." Molecular cancer therapeutics 15, no. 6 (June 2016): 1344-1352.

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Nagaraja, AS, Dorniak, PL, Sadaoui, NC, Kang, Y, Lin, T, Armaiz-Pena, G, Wu, SY, Rupaimoole, R, Allen, JK, Gharpure, KM, Pradeep, S, Zand, B, Previs, RA, Hansen, JM, Ivan, C, Rodriguez-Aguayo, C, Yang, P, Lopez-Berestein, G, Lutgendorf, SK, Cole, SW, and Sood, AK. "Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis." Oncogene 35, no. 18 (May 2016): 2390-2397.

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Kang, Y, Nagaraja, AS, Armaiz-Pena, GN, Dorniak, PL, Hu, W, Rupaimoole, R, Liu, T, Gharpure, KM, Previs, RA, Hansen, JM, Rodriguez-Aguayo, C, Ivan, C, Ram, P, Sehgal, V, Lopez-Berestein, G, Lutgendorf, SK, Cole, SW, and Sood, AK. "Adrenergic Stimulation of DUSP1 Impairs Chemotherapy Response in Ovarian Cancer." Clinical cancer research : an official journal of the American Association for Cancer Research 22, no. 7 (April 2016): 1713-1724.

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