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Liping Feng, MD

Assistant Professor of Obstetrics and Gynecology
Campus Mail: Box 103208, Durham, NC 27710
Phone: (919) 613-1459
Email: feng0007@mc.duke.edu

Education and Training

  • M.D., Harbin Medical University (China), 1997

Research

My research has focused on understanding the mechanisms of pregnancy complications associated with infection and maternal chemical exposures. These works are translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of adverse birth outcomes.

Liping Feng, MD, devotes her entire career to improving pregnancy outcomes through innovative research. Dr. Feng conducts both basic science/laboratory research, as well as participates in clinical studies. Her laboratory has focused on understanding the mechanisms of preterm birth, which is an important cause of perinatal and neonates’ mortality and morbidity. Currently, she has three lines of investigation focused on the roles of inflammation/infection, genetic variation, and environmental exposure in pregnancy complications, such as preterm birth and preeclampsia. This work is translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of pregnancy complications.

In addition, Dr. Feng has established an international collaboration in Global Women’s Health. She has recently affiliated with the Duke Global Health Institute (DGHI) and participates in a DGHI research. She has an interest in DGHI education, and service or policy initiatives, including mentoring and teaching graduate and professional students on fieldwork and research.

Projects

  • Understanding chemical exposure of PFBS during pregnancy and birth outcomes using in vitro and in vivo models. Using these models established in my lab, we could also test other environmental exposures

  • Investigating the impact of E-waste recycling and birth outcomes in China (Global health)

  • Building a novel in vitro placental model (collaboration with BME) to explore the mechanisms of ZIKA virus in utero transmission

  • Determine the roles of an understudied bacteria, Ureaplasma, in pregnancy

Publications

Ye, Y, Zhou, Q, Feng, L, Wu, J, Xiong, Y, and Li, X. "Maternal serum bisphenol A levels and risk of pre-eclampsia: a nested case-control study." European journal of public health 27, no. 6 (December 2017): 1102-1107.

Full Text

Smrtka, MP, Feng, L, Murtha, AP, and Grotegut, CA. "Thrombin-Induced Inflammation in Human Decidual Cells Is Not Affected By Heparin." Reproductive sciences (Thousand Oaks, Calif.) 24, no. 8 (August 2017): 1154-1163.

Full Text

Wang, X, Ouyang, F, Feng, L, Wang, X, Liu, Z, and Zhang, J. "Maternal Urinary Triclosan Concentration in Relation to Maternal and Neonatal Thyroid Hormone Levels: A Prospective Study." Environmental health perspectives 125, no. 6 (June 27, 2017): 067017-.

Full Text

Ju, R, Siddiqui, N, Garrett, J, Feng, L, and Heit, M. "A validated translation of a survey for measuring incontinence knowledge in Chinese-speaking American immigrants." International urogynecology journal 28, no. 6 (June 2017): 851-856.

Full Text

Allen, TK, Feng, L, Marinello, W, Buhimischi, IA, and Murtha, AP. "Progestins Inhibit IL1 beta Induced MMP9 Activity and GM-CSF Production from Primary Chorion Cells." March 2017.

Scholars@Duke

Feng, L, Antonia, A, Murtha, A, and Ko, D. "Racial Disparity in Ureaplasma Parvum Induced Inflammatory Responses." March 2017.

Scholars@Duke

Feng, L, Jayes, FL, Johnson, LNC, Schomberg, DW, and Leppert, PC. "Biochemical Pathways and Myometrial Cell Differentiation Leading to Nodule Formation Containing Collagen and Fibronectin." Current protein & peptide science 18, no. 2 (January 2017): 155-166.

Full Text

Meng, Y, Murtha, AP, and Feng, L. "Progesterone, Inflammatory Cytokine (TNF-α), and Oxidative Stress (H2O2) Regulate Progesterone Receptor Membrane Component 1 Expression in Fetal Membrane Cells." Reproductive sciences (Thousand Oaks, Calif.) 23, no. 9 (September 2016): 1168-1178.

Full Text

Potts, LC, Feng, L, Seed, PC, Jayes, FL, Kuchibhatla, M, Antczak, B, Nazzal, MK, and Murtha, AP. "Inflammatory Response of Human Gestational Membranes to Ureaplasma parvum Using a Novel Dual-Chamber Tissue Explant System." Biology of reproduction 94, no. 5 (May 2016): 119-.

Full Text

Kim, E, Allen, TK, Feng, L, Nazzal, MK, and Murtha, AP. "The Effect of Cytokines on Neutrophil Gelatinase-Associated Lipocalin (NGAL) mRNA Expression in a Cytotrophoblast Cell Line." March 2016.

Scholars@Duke

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