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Susan Kay Murphy, PhD

Property title
Associate Professor in Obstetrics and Gynecology
Campus Mail: 119 B Wing LSRC, 308 Research Drive, Durham, NC 27708
Phone: (919) 681-3423
Email: susan.murphy@duke.edu

Ovarian and cervical cancer epigenetics, imprinted genes in ovarian and cervical cancers, identification of methylation biomarkers of disease, ovarian cancer stem cells, chemotherapeutic response in ovarian cancer, tumor dormancy, the influence of the in utero environment on DNA methylation and risk of disease.

Education and Training

  • Ph.D., Wake Forest University, 1998
  • B.A., University of North Carolina at Charlotte, 1992

Selected Grants and Awards

Publications

Kantor, B, Tagliafierro, L, Gu, J, Zamora, ME, Ilich, E, Grenier, C, Huang, ZY, Murphy, S, and Chiba-Falek, O. "Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD." Molecular Therapy : the Journal of the American Society of Gene Therapy 26, no. 11 (November 2018): 2638-2649.

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Sorrow, P, Maguire, R, Murphy, SK, Belcher, SM, and Hoyo, C. "Elevated metabolites of acetaminophen in cord blood of children with obesity." Pediatric Obesity (September 25, 2018).

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Do, EK, Zucker, NL, Huang, ZY, Schechter, JC, Kollins, SH, Maguire, RL, Murphy, SK, Hoyo, C, and Fuemmeler, BF. "Associations between imprinted gene differentially methylated regions, appetitive traits and body mass index in children." Pediatric Obesity (September 19, 2018).

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Gomih, A, Smith, JS, North, KE, Hudgens, MG, Brewster, WR, Huang, Z, Skaar, D, Valea, F, Bentley, RC, Vidal, AC, Maguire, RL, Jirtle, RL, Murphy, SK, and Hoyo, C. "DNA methylation of imprinted gene control regions in the regression of low-grade cervical lesions." International Journal of Cancer 143, no. 3 (August 2018): 552-560.

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Gao, L, Liu, X, Millstein, J, Siegmund, KD, Dubeau, L, Maguire, RL, Jim Zhang, J, Fuemmeler, BF, Kollins, SH, Hoyo, C, Murphy, SK, and Breton, CV. "Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes." Clinical Epigenetics 10, no. 1 (July 20, 2018): 98-null.

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Green, AJ, Hoyo, C, Mattingly, CJ, Luo, Y, Tzeng, J-Y, Murphy, SK, Buchwalter, DB, and Planchart, A. "Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study." International Journal of Obesity (2005) 42, no. 7 (July 2018): 1285-1295.

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Tindula, G, Murphy, SK, Grenier, C, Huang, Z, Huen, K, Escudero-Fung, M, Bradman, A, Eskenazi, B, Hoyo, C, and Holland, N. "DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure." July 2018.

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Bradley, MS, Burke, EE, Grenier, C, Amundsen, CL, Murphy, SK, and Siddiqui, NY. "A genome-scale DNA methylation study in women with interstitial cystitis/bladder pain syndrome." Neurourology and Urodynamics 37, no. 4 (April 2018): 1485-1493.

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Schrott, R, and Murphy, SK. "Folic acid throughout pregnancy: too much?." The American journal of clinical nutrition 107, no. 4 (April 2018): 497-498.

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Benjamin Neelon, SE, White, AJ, Vidal, AC, Schildkraut, JM, Murtha, AP, Murphy, SK, Kullman, SW, and Hoyo, C. "Maternal vitamin D, DNA methylation at imprint regulatory regions and offspring weight at birth, 1 year and 3 years." International Journal of Obesity (2005) 42, no. 4 (April 2018): 587-593.

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