ASCO and ESMO Value Frameworks May Be Beneficial in Determining Best Maintenance Therapies for Ovarian Cancer
In recent years, the Food and Drug Administration approved several maintenance therapies for the management of platinum-sensitive recurrent ovarian cancer. Clinical trials that led to these approvals involved bevacizumab (Avastin), TKIs, or PARP inhibitors.
To access the value of the maintenance therapies and biomarkers to direct treatment, investigators from Duke University Medical Center; David Geffen School of Medicine at UCLA in Los Angeles; The Ohio State University, James Cancer Hospital in Columbus, Ohio; and Memorial Sloan Kettering Cancer Center in New York City, used the American Society of Clinical Oncology (ASCO)’s Net Health Benefit (NHB) and the European Society of Medical Oncology (ESMO)’s Magnitude of Clinical Benefit Scale (MCBS).
In recent years, the Food and Drug Administration approved several maintenance therapies for the management of platinum-sensitive recurrent ovarian cancer. Clinical trials that led to these approvals involved bevacizumab (Avastin), TKIs, or PARP inhibitors.
To access the value of the maintenance therapies and biomarkers to direct treatment, investigators from Duke University Medical Center; David Geffen School of Medicine at UCLA in Los Angeles; The Ohio State University, James Cancer Hospital in Columbus, Ohio; and Memorial Sloan Kettering Cancer Center in New York City, used the American Society of Clinical Oncology (ASCO)’s Net Health Benefit (NHB) and the European Society of Medical Oncology (ESMO)’s Magnitude of Clinical Benefit Scale (MCBS).
— Published on OncLive.com