Cassandra K. Kisby, MD, MS, is an Assistant Professor of Obstetrics and Gynecology and the Director of Duke’s Genitourinary Congenital Anatomic Differences (GU CARES) Program. This is a multi-disciplinary program that cares for women nationally and internationally who have differences in their urogenital organs, such as uterovaginal agenesis, vaginal septa, uterine anomalies, and exstrophy. Given her clinical expertise in genitourinary congenital abnormalities, her research also focuses on novel surgical and regenerative techniques for patients with congenital anatomic differences of the genitourinary tract, evidence-based device creation using 3D printing, and outcomes research for vaginoplasty procedures.
Dr. Kisby’s research focuses on two areas: women's health regenerative medicine and genitourinary congenital anomalies, which are complements to her reconstructive surgery clinical practice. Dr. Kisby has a Master’s in Biomedical Research, Certificate in Clinical and Translational Research, and Certificate in Regenerative Medicine, which she completed at Mayo Clinic. At Duke, she collaborates with Plastic Surgeons, Urologists, Biomedical Engineers, and Materials Science experts to evaluate novel solutions to unmet patient needs in the area of pelvic reconstructive surgery. She is part of the K12 Urologic Research Career Development Program to advance research in benign urologic disease. Her projects under this grant are focused on applying regenerative biologics to vaginal mesh exposure (a complication of pelvic reconstructive surgery), pelvic tissue regeneration, and other genitourinary disorders. She works with a variety of regenerative biologics, including exosomes, platelet rich plasma, biogels, and biostimulators.